Predictive value of intra-hepatectomy ICGR15 of the remnant liver for post-hepatectomy liver failure in hemi-hepatectomy: a prospective study [PDF]
Background and objective Post-hepatectomy liver failure (PHLF) is one of the major complications following hepatectomy for hepatocellular carcinoma (HCC). Early identification and precise prediction of PHLF are essential for effective management.
Tianyi Liang +14 more
doaj +3 more sources
Post-hepatectomy liver failure
ABSTRACT INTRODUCTION: Post-hepatectomy liver failure (PHLF) is one of the most serious complications of liver resection and is associated with high morbidity and mortality rates. PRESENTATION OF CASE: We report a ...
Lhuaire M. +5 more
openaire +3 more sources
Acute kidney injury after major hepatectomy: association with postoperative complications and post-hepatectomy liver failure [PDF]
Background Patients undergoing liver resections are at increased risk of acute kidney injury (AKI). The objective of this study was to examine AKI after major hepatectomy and the associated risk of adverse postoperative outcomes, including post ...
Sandström, Per +33 more
core +2 more sources
Approaching Thrombospondin-1 as a Potential Target for Mesenchymal Stromal Cells to Support Liver Regeneration after Partial Hepatectomy in Mouse and Humans [PDF]
Extended liver resection carries the risk of post-surgery liver failure involving thrombospondin-1-mediated aggravation of hepatic epithelial plasticity and function.
Lysann Tietze +8 more
doaj +3 more sources
Hospital Volume and Post‐Hepatectomy Liver Failure After Major Hepatectomy [PDF]
ABSTRACT Background Post‐hepatectomy liver failure (PHLF) following major hepatectomy (MH) increases the risk of morbidity and death. The relationship between institutional MH volume, PHLF, and outcomes is not well characterized. Methods
Xane D. Peters +8 more
openaire +4 more sources
Multivariable prognostic models for post-hepatectomy liver failure: An updated systematic review [PDF]
BACKGROUND Partial hepatectomy continues to be the primary treatment approach for liver tumors, and post-hepatectomy liver failure (PHLF) remains the most critical life-threatening complication following surgery. AIM To comprehensively review the PHLF prognostic models developed in recent years and objectively assess the ...
Wang, Xiao +8 more
openaire +4 more sources
Development of a Porcine Model of Post-Hepatectomy Liver Failure
The aim of this study was to develop a porcine model of post-operative liver failure (POLF) that could accurately reproduce all the neurological and metabolic parameters of the corresponding clinical syndrome that may develop after extensive liver resections.In our model, we induced POLF by combining extended left hepatectomy and ischemia of the small ...
Nikolaos, Arkadopoulos +10 more
core +5 more sources
Abnormal Distribution and Upregulation of Tenascin-C mRNA Expression in the Liver of 90% Hepatectomy Rats are Related to Post-hepatectomy Liver Failure [PDF]
Background: Post-hepatectomy liver failure (PHLF) is the most serious complication after extended hepatectomy, with a high perioperative mortality rate. Matricellular protein tenascin-C (TNC) has been related to blood flow change and inflammation.
Xinlan Ge +4 more
doaj +2 more sources
Establishing the clinical relevance of grade A post‐hepatectomy liver failure [PDF]
AbstractIntroductionThe International Study Group of Liver Surgery's criteria stratifies post‐hepatectomy liver failure (PHLF) into grades A, B, and C. The clinical significance of these grades has not been fully established.MethodsThe American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) hepatectomy‐targeted database ...
Dominic J. Vitello +7 more
openaire +3 more sources
Post hepatectomy Liver Failure (PHLF) is a fatal complication, especially after major liver resection. Insufficient remnant liver volume is a common cause of postoperative liver failure.
Anh T Pham +8 more
doaj +2 more sources

