Results 151 to 160 of about 3,012,710 (285)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Correction: Socioeconomic position and the influence of food portion size on daily energy intake in adult females: two randomized controlled trials. [PDF]
Int J Behav Nutr Phys Act, 2023 Langfeld T +4 more
europepmc +1 more source
How will baby boomer retirements affect teacher labor markets? [PDF]
The authors estimate teacher demand and supply through 2020 to gauge the impact of baby boomer retirements on the demand for new teachers. They find that the projected demand will accelerate through at least 2020, and a good portion of this increase will
Daniel Aaronson, Katherine Meckel
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Estimation of Plate and Bowl Dimensions for Food Portion Size Assessment in a Wearable Sensor System. [PDF]
IEEE Sens J, 2023 Raju VB, Hossain D, Sazonov E.
europepmc +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Development of a Digital Photographic Food Atlas as a Portion Size Estimation Aid in Japan. [PDF]
Nutrients, 2022 Shinozaki N +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A short training program improves the accuracy of portion-size estimates in future dietitians
Archivos Latinoamericanos de Nutrición, 2007 The objective of this study was to determine whether a short training program, using real foods, would decreased their portion-size estimation errors after training. 90 student volunteers (20.18±0.44 y old) of the University of the Basque Country (Spain)
Marta Arroyo +3 more
doaj