Results 51 to 60 of about 613,875 (232)

Validation of Aspartate Aminotransferase to Platelet Ratio for Diagnosis of Hepatic Fibrosis and Prognostic Prediction of Infants with Biliary Atresia after Portoenterostomy

, 2018
Objectives: We aimed to evaluate the role of aspartate aminotransferase to platelet ratio in the diagnosis of liver fibrosis and its prognosis after surgery in infants with biliary atresia.
F. Imanzadeh, N. Dara, P. Rohani, B. Emadi, S. Sanii, Mohadese Sadat Mousavi Khorshidi, A. Hosseini   +6 more
semanticscholar   +1 more source

Unveiling Hepatic Protein Alterations in Neonatal and Infant Biliary Atresia

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1584-1596, June 2026.
Pediatric populations differ from adults in drug elimination capacity. While current scaling methods account for enzyme and transporter maturation, they overlook comorbidities, such as biliary atresia (BA), a liver disease appearing within the first 2–8 weeks of life that can progress to cirrhosis.
Zubida M. Al‐Majdoub, Martyn Howard, Brahim Achour, Jill Barber, Naved Alizai, Amin Rostami‐Hodjegan   +5 more
wiley   +1 more source

Biliary atresia recent insight

Egyptian Pediatric Association Gazette, 2018
Biliary atresia (BA) is a rare disease characterized by ascending obstruction of bile ducts that exclusively affects newborn infants. The etiology of the disease is not known. BA is considered to be a phenotype resulting from several pathogenic processes
Ramy Mohamed Ghazy, Nermin M. Adawy, Mohamed Ahmed Khedr, Mohamed Mostafa Tahoun   +3 more
doaj   +1 more source

Newly Formed Hepatic Masses in Children with Biliary Atresia after Kasai Hepatic Portoenterostomy

, 2011
H. Song, Y. Suh
semanticscholar   +2 more sources

Correlation of Transient Elastography and Progression of Cirrhosis in Longterm Survivors of Biliary Atresia

Siriraj Medical Journal, 2021
Objective: This study aimed to use transient elastography (TE) to evaluate the correlation between liver stiffness measure (LSM) and functional status of native liver in longterm follow-up of pediatric patients with biliary atresia (BA). Methods: Twenty
Witsanee Srisuwan, Wison Laochareonsuk, Panu Wetwittayakhlang, Supika Kritsaneepaiboon, Surasak Sangkhathat   +4 more
doaj   +1 more source

Effect of General Anesthesia on Liver and Spleen Stiffness for Predicting High‐Risk Varices in Biliary Atresia

Hepatology Research, Volume 56, Issue 2, Page 223-232, February 2026.
In children with biliary atresia (BA), breath‐holding during liver and spleen stiffness (LS and SS) measurement is often difficult, raising concerns about measurement reliability in the awake state. We investigated whether performing LS and SS measurements under general anesthesia—when brief ventilation pauses are possible—could improve diagnostic ...
Shinya Yokoyama, Takashi Honda, Yoji Ishizu, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Masanao Nakamura, Hiroo Uchida, Hiroki Kawashima   +11 more
wiley   +1 more source

Evaluation of miRNA Expression in Pediatric Cirrhosis Caused by BA and PFIC

BioMed Research International, Volume 2026, Issue 1, 2026.
Liver cirrhosis is one of the most common causes of death for pediatric patients with cholestasis. Because microRNA (miRNA) plays a part in the pathogenesis of the disease, comparing the changes in miRNA expression in cholestatic patients with liver cirrhosis could be helpful for therapeutic or prognostic purposes.
Fatemeh Khosravi, Ramin Yaghobi, Afsoon Afshari, Nasrin Motazedian, Bita Geramizadeh, Tayebeh Kazemi, Seyed Mohsen Dehghani, Baisakhi Banerjee   +7 more
wiley   +1 more source

A phase 2 trial of N-Acetylcysteine in Biliary atresia after Kasai portoenterostomy

Contemporary Clinical Trials Communications, 2019
Background: Biliary atresia (BA) is a life-threatening liver disease of infancy, characterized by extrahepatic biliary obstruction, bile retention, and progressive liver injury. The Kasai portoenterostomy (KP) is BA's only nontransplant treatment.
Mary Elizabeth M. Tessier, Benjamin L. Shneider, Mary L. Brandt, Dana N. Cerminara, Sanjiv Harpavat   +4 more
doaj   +1 more source

Safe and Early Primary Closure of Open Abdomen in Pediatric Liver Transplantation Using a Doppler‐Guided Tension Relief Strategy and Enhanced Wound Environment

Journal of Transplantation, Volume 2026, Issue 1, 2026.
Pediatric liver transplantation (LT) with large‐for‐size (LFS) grafts frequently necessitates open abdomen (OA) management due to donor–recipient graft size mismatch, increasing the risk of delayed closure and frequently requires the use of permanent prosthetic materials, together compounding the risk of postoperative infection.
Michael Gurevich, Tomer Mendelson, Haya Fischer, Elhanan Nahum, Avichai Weissbach, Yael Glassberg Mozer, Orith Waisbourd-Zinman, Sigal Aizner, Eviatar Nesher, Moris Topaz, Richa Sharma   +10 more
wiley   +1 more source

Biliary Atresia Patients With Successful Kasai Portoenterostomy Can Present With Features of Obliterative Portal Venopathy.

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2020
OBJECTIVES Study of liver explants of biliary atresia (BA) patients with successful Kasai portoenterostomy (KP). METHODS Pathology and medical records of BA liver explants from January 2009 to June 2018 with successful KP were reviewed along with ...
K. Patel, S. Harpavat, Z. Khan, S. Dhingra, Norma M. Quintanilla, Mihail Firan, J. Goss   +6 more
semanticscholar   +1 more source