Results 191 to 200 of about 27,357 (215)
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Invasive fungal infection following venetoclax and posaconazole co‐administration
British Journal of Haematology, 2023The co‐administration of venetoclax, a BCL‐2 inhibitor, with a mould‐active azole, such a posaconazole, has potential to both prevent invasive fungal infection (IFI) and reduce the required treatment dose, and cost, of venetoclax. Posaconazole drug‐level
G. Reynolds +3 more
semanticscholar +1 more source
Drugs of Today, 2005
Invasive fungal infections are occurring with increasing frequency secondary to medical advances in the areas of transplantation, cancer management and autoimmune diseases. Unfortunately, the currently available antifungal armamentarium does not meet the increasing needs of managing infection in these complex patient populations.
Elizabeth S, Dodds Ashley +1 more
openaire +4 more sources
Invasive fungal infections are occurring with increasing frequency secondary to medical advances in the areas of transplantation, cancer management and autoimmune diseases. Unfortunately, the currently available antifungal armamentarium does not meet the increasing needs of managing infection in these complex patient populations.
Elizabeth S, Dodds Ashley +1 more
openaire +4 more sources
Leukemia and Lymphoma, 2022
Posaconazole is indicated for antifungal prophylaxis in hematology patients at high-risk of invasive fungal infections (IFI). Consensus guidelines recommend maintaining steady-state trough concentrations above 0.7 mg/L; however, upto one-third of ...
Jessica Bui +3 more
semanticscholar +1 more source
Posaconazole is indicated for antifungal prophylaxis in hematology patients at high-risk of invasive fungal infections (IFI). Consensus guidelines recommend maintaining steady-state trough concentrations above 0.7 mg/L; however, upto one-third of ...
Jessica Bui +3 more
semanticscholar +1 more source
International Journal of Dermatology, 2021
Terbinafine and itraconazole are the most commonly used oral antifungals to treat onychomycosis and superficial dermatomycoses. Recently, poor response to oral terbinafine has been reported.
Aditya K. Gupta +2 more
semanticscholar +1 more source
Terbinafine and itraconazole are the most commonly used oral antifungals to treat onychomycosis and superficial dermatomycoses. Recently, poor response to oral terbinafine has been reported.
Aditya K. Gupta +2 more
semanticscholar +1 more source
Journal of Oncology Pharmacy Practice, 2021
Introduction Calcineurin inhibitors are commonly used in hematopoietic stem cell transplant (HSCT) patients to prevent graft versus host disease, but as CYP3A4 substrates they are frequently involved in drug-drug interactions.
Tina M Gu +3 more
semanticscholar +1 more source
Introduction Calcineurin inhibitors are commonly used in hematopoietic stem cell transplant (HSCT) patients to prevent graft versus host disease, but as CYP3A4 substrates they are frequently involved in drug-drug interactions.
Tina M Gu +3 more
semanticscholar +1 more source
Expert Opinion on Pharmacotherapy, 2021
Introduction Invasive fungal diseases (IFDs) are a significant cause of morbidity and mortality among immunocompromised patients. Safe and effective antifungal medications used for prophylaxis and treatment are pivotal in their management.
P. Panagopoulou, E. Roilides
semanticscholar +1 more source
Introduction Invasive fungal diseases (IFDs) are a significant cause of morbidity and mortality among immunocompromised patients. Safe and effective antifungal medications used for prophylaxis and treatment are pivotal in their management.
P. Panagopoulou, E. Roilides
semanticscholar +1 more source
Expert Opinion on Drug Metabolism & Toxicology, 2020
Introduction Invasive fungal infections (IFIs) are associated with a high morbidity and mortality and their incidence is rising. Posaconazole is a triazole antifungal drug that has an important place in the prophylaxis and salvage treatment of these ...
R. Van Daele, I. Spriet, J. Maertens
semanticscholar +1 more source
Introduction Invasive fungal infections (IFIs) are associated with a high morbidity and mortality and their incidence is rising. Posaconazole is a triazole antifungal drug that has an important place in the prophylaxis and salvage treatment of these ...
R. Van Daele, I. Spriet, J. Maertens
semanticscholar +1 more source