Results 81 to 90 of about 27,357 (215)
Fungal infections of the central nervous system: A review of fungal pathogens and treatment [PDF]
, 2007 Multiple factors influence the outcome of fungal infection of the central nervous system (CNS). The host and the pathogen in concert with drug delivery across the blood-brain barrier and drug activity are key factors in outcome.
Dancer, C., Redmond, A., Woods, M. L.
core +1 more source
Posaconazole Serum Drug Levels Associated with Pseudohyperaldosteronism.
Clinical Infectious Diseases, 2019 BACKGROUND Posaconazole tablets are well tolerated and efficacious in the prophylaxis and treatment of aspergillosis, mucormycosis, and other invasive fungal infections.
M. Nguyen +7 more
semanticscholar +1 more source
Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review
Journal of the European Academy of Dermatology and Venereology, EarlyView.Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta +5 more
wiley +1 more source
Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]
, 2018 Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo +4 more
core +1 more source
The Clinically Approved Antifungal Drug Posaconazole Inhibits Human Cytomegalovirus Replication
Antimicrobial Agents and Chemotherapy, 2020 Posaconazole (PCZ) is a clinically approved drug used predominantly for prophylaxis and salvage therapy of fungal infections. Here, we report its previously undescribed anti-human cytomegalovirus (HCMV) activity.
B. Mercorelli +6 more
semanticscholar +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 381-392, February 2026.Model‐informed precision dosing (MIPD) of tacrolimus in renal allograft recipients, evaluated in silico, demonstrated improved (time to and) probability of target concentration attainment and smaller deviations from target range. Using simulated tacrolimus concentration‐time profiles, a study of 200 patients was predicted to have sufficient power to ...
Dirk R.J. Kuypers +6 more
wiley +1 more source
Food, Acid Supplementation and Drug Absorption - a Complicated Gastric Mix: a Randomized Control Trial. [PDF]
, 2019 PURPOSE:The purpose of this study was to determine the impact of food on gastric pH and the ability of over the counter betaine hydrochloride (BHCl) acid to reacidify gastric pH after food-induced elevations in gastric pH.
Benet, Leslie Z +2 more
core
Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]
, 2012 This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Beyer, Jörg +11 more
core +1 more source
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Essential oils with anti‐HSV‐1 activity were identified through literature review and tested against Candida to develop a formulation for co‐infections. The blend was assessed for anti‐inflammatory properties, allergenic potential via standardized BAT, and overall antiviral efficacy.
Maura Di Vito +11 more
wiley +1 more source
Drug Design, Development and Therapy, 2010 Emily Zoller, Connie Valente, Kyle Baker, Michael E KlepserFerris State University College of Pharmacy, Kalamazoo, Michigan, USAAbstract: Posaconazole is an extended-spectrum azole antifungal that exhibits activity against a broad range of fungal ...
Emily Zoller +3 more
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