Results 91 to 100 of about 6,829 (292)

Homogenization of a Continuously Microperiodic Multidimensional Medium

open access: yesTrends in Computational and Applied Mathematics, 2018
The asymptotic homogenization method is applied to obtain formal asymptotic solution and the homogenized solution of a Dirichlet boundary-value problem for an elliptic equation with rapidly os- cillating coefficients.
Marcos Pinheiro Lima   +2 more
doaj   +1 more source

Metallothionein‐Inspired Asymmetric Heteroatom Doping of Single‐Atom Nanozymes for Multi‐Enzyme Biocatalysis

open access: yesAdvanced Science, EarlyView.
A metallothionein‐inspired heteroatom doping strategy is reported to construct asymmetric Fe single‐atom catalysts, which display markedly enhanced multi‐enzyme activities—including NADH oxidase‐, oxidase‐, peroxidase‐, and catalase‐like activities. This high multi‐enzyme efficiency arises from atomically dispersed Fe from biomineralization, the large ...
Kaijuan Chen   +6 more
wiley   +1 more source

Experimental Joint Estimation of Phase and Phase Diffusion Via Deterministic Bell Measurements

open access: yesAdvanced Science, EarlyView.
This work employs Bell measurement, a form of entangling measurement, to estimate both the phase and its fluctuations in an optical interferometer. By incorporating a novel quantum effect at the measurement stage, the proposed method achieves the ultimate precision limit and demonstrates the significant potential of entangling measurements in multi ...
Ben Wang   +4 more
wiley   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma   +15 more
wiley   +1 more source

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

open access: yesAdvanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu   +12 more
wiley   +1 more source

Nucleoside‐Based Hydrogel Platform Synergizes with Photothermal Effects for Enhanced Biofilm Eradication Against Periodontitis

open access: yesAdvanced Science, EarlyView.
A synergistic antibiofilm hydrogel platform (ZBAg@FNP) is developed by encapsulating an organic small‐molecule photothermal agent (FNP) within a silver ion‐mediated supramolecular hydrogel (ZBAg), enabling photothermal disruption of biofilm integrity and controlled Ag⁺ ion release upon irradiation.
Yinghui Wen   +8 more
wiley   +1 more source

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