Results 81 to 90 of about 327,787 (287)

Challenging Behaviors in Young Children: The Father\u27s Role [PDF]

, 2004
In this study, the authors examined the parenting practices, developmental expectations, and stress levels of 136 fathers and the challenging and prosocial behaviors of their 1- to 5-year-old children.
Burbach, Ann D, Fox, Robert A., Nicholson, Bonnie C   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Positive Communication: Classroom, Workplace, And Parenting

Journal of Innovation in Polytechnic Education
Education provides students with the important, domain-specific skills required for their chosen career (e.g., nursing, engineering, etc). However, institutions of higher education are also tasked with developing transferable or “soft” skills which will
Lynne Kennette, Lisa Rausch
doaj   +1 more source

Strengthening Families: Parents\u27 Voices on Discipline and Child Rearing [PDF]

, 2011
This qualitative study conducted semi-structured, multi-session focus groups and interviews with twenty-seven participants to explore in-depth, participant constructs of child discipline and punishment methods and reasons for the continuing support for ...
Breshears, Elizabeth M
core   +1 more source

The Feasibility, Appropriateness, Meaningfulness, and Effectiveness of Parenting and Family Support Programs Delivered in the Criminal Justice System: A Systematic Review [PDF]

, 2018
Children whose parents are involved in the criminal justice system (CJS) are at increased risk of developing social, emotional, and behavioural difficulties and are more likely than their peers to become involved in the CJS themselves.
A Mejia, A Mills, A Pearson, AB *Loper, AD Trice, AL *Miller, AL Miller, AR *Moore, AS *Skar, AT *Menting, AT *Scudder, B Brooks-Gordon, C *Rossiter, C Bonell, Carol Emslie, DH Dallaire, DL Fixsen, DP Farrington, E *McCrudden, Elizabeth Gilchrist, EM Ingoldsby, F Bunn, GL *Landreth, GL *Wilczak, HC Hoffmann, HL *Surratt, J Arditti, J Barlow, J Dretzke, J Murray, J Murray, J Poehlmann, JC Marsh, JJ *LaRosa, JL *Sandifer, JM *Eddy, JM Eddy, JW *Shortt, JW Kaminski, K *Harrison, K *Wilson, K Buston, K Williams, KA Whittaker, KE McPherson, Kerri E. McPherson, KM Miller, LS *Urban, M Brown, M Furlong, M Glover, M Purvis, ML *Robbers, MR Sanders, MR Sanders, MT Berg, P *Gonzalez, PJ *Thompson, R *Meek, RD Morgan, S *Block, S *Bushfield, S *Frye, SI Mignon, SS *Kennon, TA *Cornille, TG Mazzucchelli, Victoria Troy, VJ *Palusci, ZL *Harris   +69 more
core   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Unlocking the Power of Parenting: Unraveling How Family Atmosphere and Parenting Styles Impact the Pivotal Role in Bullying Behavior

Studia Psychologica
Bullying at school negatively affects the class environment as well as all young people who participate in the bullying. One of the most important factors related to bullying is family. In the current study, the effect of family atmosphere and parenting
Mária Dědová, Gabriel Baník
doaj   +1 more source

Perceptions of parenting practices and psychological variables of elite and sub-elite youth athletes [PDF]

, 2019
Drawing from the model of parental involvement in sport, the overall purpose was to examine the associations of perceptions of parenting practices (encouragement, reinforcement, instruction, and role modeling) and athletes’ psychological variables (self ...
Calmeiro, Luis, Rosado, António, Serpa, Sidónio, Silva, Carlos, Teques, Pedro   +4 more
core   +4 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source