Results 111 to 120 of about 5,619,071 (301)

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

Positive solutions for second-order multi-point boundary-value problems at resonance in Banach spaces

Electronic Journal of Differential Equations, 2011
In this article, we study the existence and multiplicity of positive solutions for a nonlinear second-order multi-point boundary-value problem at resonance in Banach spaces. The arguments are based upon a specially constructed equivalent equation and
Weihua Jiang, Bin Wang
doaj  

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Monotone and convex positive solutions for fourth-order multi-point boundary value problems

Boundary Value Problems, 2011
The existence results of multiple monotone and convex positive solutions for some fourth-order multi-point boundary value problems are established. The nonlinearities in the problems studied depend on all order derivatives. The analysis relies on a fixed
Chunfang Shen, Liu Yang, Weiguo Zhang
doaj  

Martin boundary and positive solutions of some boundary value problems [PDF]

, 1965
Evgeny B. Dynkin
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Uniqueness of positive solutions of parabolic equations with unbounded coefficients [PDF]

, 1967
D. G. Aronson, P. Besala
openalex   +1 more source

Positive Solutions of an Emden-Fowler Equation

Journal of Mathematical Analysis and Applications, 1994
Some new results concerning asymptotic integration and global existence of positive solutions of the Emden-Fowler equation \((r(t)x')' = P(t) | x |^{\nu-1} x\) are given. These results improve well known results of this area. Some applications to certain elliptic problems are given, too.
openaire   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Existence of positive solutions for self-adjoint boundary-value problems with integral boundary conditions at resonance

Electronic Journal of Differential Equations, 2011
In this article, we study the self-adjoint second-order boundary-value problem with integral boundary conditions, $$displaylines{ (p(t)x'(t))'+ f(t,x(t))=0,quad tin (0,1),cr p(0)x'(0)=p(1)x'(1),quad x(1)=int_0^1x(s)g(s)ds, }$$ which involves an ...
Aijun Yang, Bo Sun, Weigao Ge
doaj