Results 111 to 120 of about 5,764,328 (311)
Electronic Journal of Differential Equations, 2011 In this article, we study the existence and multiplicity of positive solutions for a nonlinear second-order multi-point boundary-value problem at resonance in Banach spaces. The arguments are based upon a specially constructed equivalent equation and
Weihua Jiang, Bin Wang
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Monotone and convex positive solutions for fourth-order multi-point boundary value problems
Boundary Value Problems, 2011 The existence results of multiple monotone and convex positive solutions for some fourth-order multi-point boundary value problems are established. The nonlinearities in the problems studied depend on all order derivatives. The analysis relies on a fixed
Chunfang Shen, Liu Yang, Weiguo Zhang
doaj
Isoperimetric Inequalities and Sharp Estimate for Positive Solution of Sublinear Elliptic Equations [PDF]
, 2010 Qiuyi Dai, Renchu He, Huaxiang Hu
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On Existence of Symmetric Positive Solutions for SSBVPs on Time Scales
, 2021 Cansel KUYUMCU, Erbil Çetin
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Electronic Journal of Differential Equations, 2011 In this article, we study the self-adjoint second-order boundary-value problem with integral boundary conditions, $$displaylines{ (p(t)x'(t))'+ f(t,x(t))=0,quad tin (0,1),cr p(0)x'(0)=p(1)x'(1),quad x(1)=int_0^1x(s)g(s)ds, }$$ which involves an ...
Aijun Yang, Bo Sun, Weigao Ge
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source