Results 121 to 130 of about 17,377,748 (367)

Monotone Positive Solution of Nonlinear Third-Order BVP with Integral Boundary Conditions

open access: yes, 2010
This paper is concerned with the following third-order boundary value problem with integral boundary conditions , where and . By using the Guo-Krasnoselskii fixed-point theorem, some sufficient conditions are obtained for the existence and nonexistence ...
Jian-Ping Sun, Hai-Bao Li
semanticscholar   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Existence of two positive solutions for a singular Neumann problem

open access: yesElectronic Journal of Differential Equations, 2014
We obtain two positive solutions for Neumann boundary problems with singularity and subcritical term, by using the Nehari method.
Jia-Feng Liao   +3 more
doaj  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Global continuum and multiple positive solutions to a p-Laplacian boundary-value problem

open access: yesElectronic Journal of Differential Equations, 2012
A p-Laplacian boundary-value problem with positive nonlinearity is considered. The existence of a continuum of positive solutions emanating from $(lambda,u)=(0,0)$ is shown, and it can be extended to $lambda=infty$.
Chan-Gyun Kim, Junping Shi
doaj  

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