Results 141 to 150 of about 17,909,648 (352)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Existence of positive solutions for superlinear p-Laplacian equations

open access: yesElectronic Journal of Differential Equations, 2015
We obtain a positive solution for a superlinear p-Laplacian equations with the Dirichlet boundary-value conditions. Our main tool is a variation of the mountain pass theorem.
Ting-Mei Gao, Chun-Lei Tang
doaj  

Positive Solution to a Nonlinear Elliptic Problem

open access: yesPotential Analysis, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Positive solutions for elliptic equations with singular nonlinearity

open access: yesElectronic Journal of Differential Equations, 2005
We study an elliptic boundary-value problem with singular nonlinearity via the method of monotone iteration scheme: $$displaylines{ -Delta u(x)=f(x,u(x)),quad x in Omega,cr u(x)=phi(x),quad x in partial Omega , }$$ where $Delta$ is the Laplacian ...
Junping Shi, Miaoxin Yao
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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