Results 141 to 150 of about 13,731,074 (335)

Positive Solutions of Quasilinear Elliptic Equations

open access: yesJournal of Mathematical Analysis and Applications, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Existence of positive solutions for self-adjoint boundary-value problems with integral boundary conditions at resonance

open access: yesElectronic Journal of Differential Equations, 2011
In this article, we study the self-adjoint second-order boundary-value problem with integral boundary conditions, $$displaylines{ (p(t)x'(t))'+ f(t,x(t))=0,quad tin (0,1),cr p(0)x'(0)=p(1)x'(1),quad x(1)=int_0^1x(s)g(s)ds, }$$ which involves an ...
Aijun Yang, Bo Sun, Weigao Ge
doaj  

Positive solutions for superlinear elliptic equations

open access: yesJournal of Mathematical Analysis and Applications, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

An elliptic problem with arbitrarily small positive solutions

open access: yesElectronic Journal of Differential Equations, 2000
We show that for each $lambda > 0$, the problem $-Delta_p u = lambda f(u)$ in $Omega$, $u = 0$ on $partial Omega$ has a sequence of positive solutions $(u_n)_n$ with $max_{Omega} u_n$ decreasing to zero.
Pierpaolo Omari, Fabio Zanolin
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Existence of positive solutions for superlinear p-Laplacian equations

open access: yesElectronic Journal of Differential Equations, 2015
We obtain a positive solution for a superlinear p-Laplacian equations with the Dirichlet boundary-value conditions. Our main tool is a variation of the mountain pass theorem.
Ting-Mei Gao, Chun-Lei Tang
doaj  

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