Results 141 to 150 of about 5,619,071 (301)

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Positive solutions for a system of second-order boundary-value problems involving first-order derivatives

Electronic Journal of Differential Equations, 2012
In this article we study the existence and multiplicity of positive solutions for the system of second-order boundary value problems involving first order derivatives $$displaylines{ -u''=f(t, u, u', v, v'),cr -v''=g(t, u, u', v, v'),cr u(0)=u'(1 ...
Kun Wang, Zhilin Yang
doaj  

Principal solutions of positive linear Hamiltonian systems [PDF]

, 1976
Don Hinton
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Another understanding of fourth-order four-point boundary-value problems

Electronic Journal of Differential Equations, 2008
In this article we investigate the existence of positive and/or negative solutions of a classes of four-point boundary-value problems for fourth-order ordinary differential equations.
Petio S. Kelevedjiev, Panos K. Palamides, Nedyu Popivanov   +2 more
doaj  

Positive solutions to a system of variational inequalities

Applied Mathematics Letters, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Bounds on 𝜆 for positive solutions of Δ𝜓+𝜆𝑓(𝑟){𝜓+𝐺(𝜓)}=0

, 1966
Daniel D. Joseph
openalex   +1 more source

Nonuniformly elliptic equations: Positivity of weak solutions [PDF]

, 1973
Charles V. Coffman, R. J. Duffin, Victor J. Mizel   +2 more
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source