Results 151 to 160 of about 17,909,648 (352)

Positive solutions of boundary-value problems for 2m-order differential equations

Electronic Journal of Differential Equations, 2003
This article concerns the existence of positive solutions to the differential equation $$ (-1)^m x^{(2m)}(t)=f(t,x(t),x'(t),dots,x^{(m)}(t)), quad ...
Yuji Liu, Weigao Ge
doaj  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Existence and Uniqueness of Positive Solution for Discrete Multipoint Boundary Value Problems. [PDF]

Int Sch Res Notices, 2014
Ma H, Ma H.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Positive solutions for Neumann boundary value problems of nonlinear second-order integro-differential equations in ordered Banach spaces

Journal of Inequalities and Applications, 2011
The paper deals with the existence of positive solutions for Neumann boundary value problems of nonlinear second-order integro-differential equations - u ″ ( t ) + M u ( t ) = f ( t , u ( t ) , ( S u ) ( t ) ) , 0
Liang Yue, Yang He
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Monotone positive solutions for p-Laplacian equations with sign changing coefficients and multi-point boundary conditions

Electronic Journal of Differential Equations, 2010
We prove the existence of three monotone positive solutions for the second-order multi-point boundary value problem, with sign changing coefficients, $$displaylines{ [p(t)phi(x'(t))]'+f(t,x(t),x'(t))=0,quad tin (0,1),cr x'(0)=-sum_{i=1}^la _ix'(xi_i)
Jianye Xia, Yuji Liu
doaj  

Positive Solutions of an Emden-Fowler Equation

Journal of Mathematical Analysis and Applications, 1994
Some new results concerning asymptotic integration and global existence of positive solutions of the Emden-Fowler equation \((r(t)x')' = P(t) | x |^{\nu-1} x\) are given. These results improve well known results of this area. Some applications to certain elliptic problems are given, too.
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Positive solutions for a system of second-order boundary-value problems involving first-order derivatives

Electronic Journal of Differential Equations, 2012
In this article we study the existence and multiplicity of positive solutions for the system of second-order boundary value problems involving first order derivatives $$displaylines{ -u''=f(t, u, u', v, v'),cr -v''=g(t, u, u', v, v'),cr u(0)=u'(1 ...
Kun Wang, Zhilin Yang
doaj