Results 151 to 160 of about 5,764,328 (311)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Existence of multiple solutions for quasilinear elliptic equations in R^N

open access: yesElectronic Journal of Differential Equations, 2014
In this article, we establish the multiplicity of positive weak solution for the quasilinear elliptic equation $$\displaylines{ -\Delta_p u+\lambda|u|^{p-2}u=f(x) |u|^{s-2 }u+h(x)|u|^{r-2}u\quad x\in \mathbb{R}^N,\cr u>0\quad x\in \mathbb{R}^N ...
Honghui Yin, Zuodong Yang
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Positive solutions for second-order m-point boundary-value problems with nonlinearity depending on the first derivative

open access: yesElectronic Journal of Differential Equations, 2006
We consider multiplicity of positive solutions for second-order m-point boundary-value problems, with the first order derivative involved in the nonlinear term. Using a fixed point theorem, we show the existence of at least three positive solutions.
Liu Yang, Xiping Liu, Chunfang Shen
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Endovascular Solution for Incorrect Stent Positioning [PDF]

open access: yesCardioVascular and Interventional Radiology, 2005
BARBERO S   +3 more
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Existence of positive solutions to three-point phi-Laplacian BVPs via homotopic deformations

open access: yesElectronic Journal of Differential Equations, 2012
Under suitable conditions and via homotopic deformation, we provide existence results for a positive solution to the three-point $phi$-Laplacian boundary-value problem $$displaylines{ -( aphi(u'))'(x)=b(x) f(x,u(x)),quad xin ( 0,1), cr u(0)=alpha u ...
Nadir Benkaci   +2 more
doaj  

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