Results 61 to 70 of about 456,539 (203)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A variational principle for stationary, axisymmetric solutions of Einstein's equations

open access: yes, 2005
Stationary, axisymmetric, vacuum, solutions of Einstein's equations are obtained as critical points of the total mass among all axisymmetric and $(t,\phi)$ symmetric initial data with fixed angular momentum.
Bartnik R   +8 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Positive solutions of a boundary value problem with integral boundary conditions [PDF]

open access: yes, 2011
We consider boundary-value problems studied in a recent paper. We show that some existing theory developed by Webb and Infante applies to this problem and we use the known theory to show how to find improved estimates on parameters μ*, λ so ...
Webb, J.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Positive Solutions for Singular p-Laplacian Fractional Differential System with Integral Boundary Conditions

open access: yesAbstract and Applied Analysis, 2014
This paper investigates the existence of positive solutions for a class of singular p-Laplacian fractional differential equations with integral boundary conditions.
Liping Wang, Zongfu Zhou, Hui Zhou
doaj   +1 more source

Higher Spin Fields in Siegel Space, Currents and Theta Functions

open access: yes, 2009
Dynamics of four-dimensional massless fields of all spins is formulated in the Siegel space of complex $4\times 4$ symmetric matrices. It is shown that the unfolded equations of free massless fields, that have a form of multidimensional Schrodinger ...
  +20 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Positive Solutions for Nonlinear Fractional Differential Equations with Boundary Conditions Involving Riemann-Stieltjes Integrals

open access: yesAbstract and Applied Analysis, 2012
We consider the existence of positive solutions for a class of nonlinear integral boundary value problems for fractional differential equations. By using some fixed point theorems, the existence and multiplicity results of positive solutions are obtained.
Jiqiang Jiang, Lishan Liu, Yonghong Wu
doaj   +1 more source

Existence and uniqueness of positive solutions for fractional differential equations

open access: yesBoundary Value Problems, 2019
By some new integral inequalities of Henry–Gronwall type, we investigate the existence and uniqueness of positive solutions for fractional differential equations.
Tao Zhu
doaj   +1 more source

Home - About - Disclaimer - Privacy