Results 91 to 100 of about 153,438 (339)

Anglo-American legal positivism: Stages of formation and development

open access: yesRUDN Journal of Law
Anglo-American legal positivism is an influential trend in modern legal thought. Understanding this framework is crucial not only for addressing gaps in scientific knowledge within political and legal doctrines but also for applying relevant developments
Maxim D. Gorbunov
doaj   +1 more source

Physical Education, Positivism, and Optimistic Claims From Achievement Goal Theorists: A Response to Pringle (2000) [PDF]

open access: green, 2001
Stuart Biddle   +3 more
openalex   +1 more source

The role of philosophical context in the development of theory: Towards methodological pluralism [PDF]

open access: yes, 2007
The research strategy dictates the major direction of the research and constitutes one of the important decisions made by the researcher. However, researchers’ understanding on theory at the outset of the research guides the design of the research.
Amaratunga, RDG   +2 more
core  

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

The Reception of Hans Kelsen\u27s Legal Theory in the United States: A Sociological Model [PDF]

open access: yes, 2008
The Essay explores the reasons underlying opposition to Hans Kelsen\u27s approach to the law within the U.S. legal academy. The vehemence with which legal scholars within the United States rejected Kelsen\u27s philosophy of law is best understood as a ...
Telman, D. A. Jeremy
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Logical Positivism and Carnap's Confirmability on the Meaningfulness of Religious Language [PDF]

open access: yes, 2018
Due to their acceptance of the verifiability principle, the only way left for logical positivists to argue for the meaningfulness of religious language was to accept some sort of emotivistic conception of it or to reduce it to the description of ...
Oya, Alberto
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

A researcher's dilemma- philosphical and methodological pluralism [PDF]

open access: yes, 2004
In many research textbooks the distinction between qualitative and quantitative research is inadvertently linked with philosophical perspectives. This in essence creates a mutually exclusive relationship between method and philosophy.
Knox, KT
core  

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