Results 71 to 80 of about 406,844 (342)

Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome

Brain Sciences, 2020
Glutamatergic receptor expression is mostly unknown in adults with fragile X syndrome (FXS). Favorable behavioral effects of negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGluR5) in fmr1 knockout (KO) mouse ...
James R. Brašić, Ayon Nandi, David S. Russell, Danna Jennings, Olivier Barret, Anil Mathur, Keith Slifer, Thomas Sedlak, Samuel D. Martin, Zabecca Brinson, Pankhuri Vyas, John P. Seibyl, Elizabeth M. Berry-Kravis, Dean F. Wong, Dejan B. Budimirovic   +14 more
doaj   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Pre-Operative Prediction of Mediastinal Node Metastasis Using Radiomics Model Based on 18F-FDG PET/CT of the Primary Tumor in Non-Small Cell Lung Cancer Patients

Frontiers in Medicine, 2021
Purpose: We investigated whether a fluorine-18-fluorodeoxy glucose positron emission tomography/computed tomography (18F-FDG PET/CT)-based radiomics model (RM) could predict the pathological mediastinal lymph node staging (pN staging) in patients with ...
Kai Zheng, Kai Zheng, Kai Zheng, Xinrong Wang, Chengzhi Jiang, Yongxiang Tang, Zhihui Fang, Jiale Hou, Zehua Zhu, Shuo Hu, Shuo Hu, Shuo Hu   +11 more
doaj   +1 more source

Minimax estimation of the Wigner function in quantum homodyne tomography with ideal detectors [PDF]

, 2006
We estimate the quantum state of a light beam from results of quantum homodyne measurements performed on identically prepared pulses. The state is represented through the Wigner function, a ``quasi-probability density'' on $\mathbb{R}^{2}$ which may take
A. Ourjoumtsev, A. P. Korostelëv, A. Zavatta, C. Helstrom, E. Wigner, F. Natterer, G. Breitenbach, G. Szegö, H. L. Trees van, I. A. Ibragimov, I. M. Johnstone, I. S. Gradshteyn, K. Vogel, L. Artiles, L. Artiles, L. Cavalier, L. Cavalier, M. Guţă, O. E. Barndorff-Nielsen, R. D. Gill, R. J. Glauber, S. R. Deans, U. Leonhardt, Y. K. Golubev, Y. K. Golubev   +24 more
core   +2 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Imaging Studies of Aging, Neurodegenerative Disease, and Alcoholism. [PDF]

, 1995
Neurodegenerative diseases such as Alzheimers disease, disorders such as alcoholism, and the aging process can lead to impaired cognitive function and dementia.
Eberling, Jamie, JAGUST, William J
core  

F-18-FDG and C-11-choline positron emission tomography in human esophago-gastric cancer : prediction of response to therapy [PDF]

, 2010
Peer reviewedPublisher ...
Hammonds, Solveig, McAteer, Dympna, Nicolson, Marianne, Park, Kenneth, Schweiger, Lutz, Sheehan, Margaret, Smith, Timothy, Suttie, Stuart, Welch, Andrew   +8 more
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Deep learning based bilateral filtering for edge-preserving denoising of respiratory-gated PET

EJNMMI Physics
Background Residual image noise is substantial in positron emission tomography (PET) and one of the factors limiting lesion detection, quantification, and overall image quality. Thus, improving noise reduction remains of considerable interest.
Jens Maus, Pavel Nikulin, Frank Hofheinz, Jan Petr, Anja Braune, Jörg Kotzerke, Jörg van den Hoff   +6 more
doaj   +1 more source

Amelioration of Glioblastoma Multiforme via the Combination of Simulated Microgravity and Oncolytic Viral Therapy

Medical Sciences Forum, 2023
Glioblastoma multiforme (GBM) is the most common aggressive malignant primary brain tumor, afflicting approximately 3.19 per 100,000 persons in the United States with an incidence 1.6 times higher in males compared to females.
Tarek Elshourbagy, James Robert Brašić
doaj   +1 more source