Results 121 to 130 of about 494,691 (265)

Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression

open access: yesAnnals of Neurology, Volume 100, Issue 4, Page 695-708, October 2026.
Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low   +11 more
wiley   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng   +4 more
wiley   +1 more source

Positron lifetime evolution during room temperature ageing in Al-Zn-Mg-(Cu)

open access: yes, 2009
The effect on the formation of vacancy-solute clusters by the addition of small percentages of Cu to Al-Zn-Mg has been studied by positron annihilation lifetime spectroscopy.
MOIA, FABIO   +4 more
core  

Photophysics of Distinguished Defect States in Bi2O2Se Thin Films

open access: yesNanophotonics, Volume 15, Issue 17, 11 September 2026.
An experimental comparison of CVD‐grown Bi2O2Se thin film and films prepared by OTG solution method with similar electrical properties reveals the defects mechanisms in Bi2O2Se thin films via OTG solution method, offering defect engineering strategies for high‐power electronics.
Xiaoran Niu   +11 more
wiley   +1 more source

Precision Oncology via Radiotherapy‐Triggered Drug Delivery: Mechanisms, Molecular Engineering, and Clinical Translation

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
This review redefines radiotherapy‐triggered drug delivery systems through structural disassembly and molecular actuation, proposing a translation‐oriented framework for dose‐correlated activation to advance clinically integrated precision oncology. ABSTRACT Radiotherapy‐triggered drug delivery systems (RDDS) promise to integrate the spatial precision ...
Jianv Jiang   +3 more
wiley   +1 more source

Cerebral oxygen extraction fraction as a physiological biomarker in vascular cognitive impairment: A study in older adults enriched for small vessel diseases

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Vascular cognitive impairment and dementia (VCID) is a common cause of cognitive impairment, yet validated biomarkers, particularly those reflecting vascular function, remain lacking. Oxygen extraction fraction (OEF), which reflects the functional status of cerebral small vessels, is a potential physiological biomarker for VCID ...
Jie Song   +20 more
wiley   +1 more source

Moisture determination in composite materials using positron lifetime techniques [PDF]

open access: yes, 1980
A technique was developed which has the potential of providing information on the moisture content as well as its depth in the specimen. This technique was based on the dependence of positron lifetime on the moisture content of the composite specimen ...
Mock, W., Jr., Holt, W. R., Singh, J. J.
core  

Retinal microvascular changes are related to indicators of glymphatic dysfunction and small vessel disease in frontotemporal dementia

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Retinal vascular alterations have been associated with cerebral small vessel disease (SVD) in frontotemporal dementia (FTD), but their relationship with magnetic resonance imaging (MRI)‐derived glymphatic‐related diffusion markers remains unclear.
William Robert Kwapong   +11 more
wiley   +1 more source

positron lifetime spectrometry

open access: yes
Citation: 'positron lifetime spectrometry' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.08752 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire   +1 more source

Mapping sex‐specific associations of adiposity with age‐related cognitive decline and multimodal Alzheimer's pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION The adiposity–cognition relationship in aging is controversial. This study aimed to assess its sex‐ and age‐specific associations with Alzheimer’s disease (AD) pathology using multimodal biomarkers. METHODS In two longitudinal cohorts (Hubei Memory and Aging Cohort Study [HMACS], n = 2,349; Alzheimer’s Disease Neuroimaging ...
Jingjing Zhang   +8 more
wiley   +1 more source

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