Results 51 to 60 of about 84,381 (266)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
THE ISSUE OF PROCEDURAL PASSIVE QUALITY IN THE PROCESSES WHICH CONCERN USUCAPTION [PDF]
Challenges of the Knowledge SocietyIn the Romanian legal system, usucaption is an original way of acquiring property rights. In court actions for the establishment of the existence of the right of ownership by virtue of usucaption, the question of the passive procedural quality has ...
Diana Andreea TOMA
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Multiple preverbation in Homeric Greek: A typological insight
CogniTextes, 2011 This paper analyses the system of multiple affixation of spatial preverbs in Homeric Greek in a typological perspective, based on Talmy’s (2000) typology of Motion event, on the work done within the Trajectoire Project (CNRS, TUL), and work on (multiple)
Caroline Imbert
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
PERMITTED SELF-HELP AS AN INSTRUMENT OF PROPERTY PROTECTION
Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej, 2016 The paper indicates instruments of possession protection as well as description of their distinctive or dependent character. The differences between an owner-like and a subsidiary owner have been defined.
Dariusz Trendel
doaj +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
“Three Loves”. A portrait of a woman destroyed by an inevitable destiny
Studia Humanitatis, 2014 “Three Loves” (1932) is A.J. Cronin’s second novel after the first successful “Hatter’s castle” (1931). The author reveals all his genius in using his pen to create stories from everyday life, dealing with social problems and interior conflicts, which ...
Fusco Amedea
doaj
Evaluation of the Embodied Cognition Hypothesis in the Formation of the Concept of "POSSESSION" in the Language of Quran [PDF]
پژوهش نامه معارف قرآنیBody cognition is one of the theoretical frameworks in cognitive sciences based on which cognition is a physical phenomenon that is formed through the interaction between body, environment, and mind.
زهرا مواظبی +2 more
doaj +1 more source