Results 61 to 70 of about 1,079,106 (302)

Violently Possessed: Johnson as the Vehicle for limiting Sentencing Enhancement under the Armed Career Criminals Act [PDF]

, 2015
This commentary previews an upcoming Supreme Court case, Johnson v. United States in which the Court will decide whether conviction for mere possession of a short-barreled shotgun qualifies as a violent felony that warrants sentence-enhancement under ...
Robe, Jonathan
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Observations on non-possessive usages of personal markers (possessive suffixes) in Nganasan

Eesti ja Soome-ugri Keeleteaduse Ajakiri, 2015
This paper aims at a systematic overview of the non-possessive usages of possessive (relational) suffixes in Nganasan. In the analyzed corpus, the non-anchoring usage types of the 3rd person suffix (including the direct anaphoric and situational usages),
Réka Zayzon
doaj   +1 more source

Drug Sale and Manufacture Arrests Reported in Alaska, 1986–2017 [PDF]

, 2018
Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug sale and manufacture arrests reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017.
Ervin, Benjamin
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Structure of the Chinese Material Value Scale: An Eastern Cultural View

Frontiers in Psychology, 2017
This study investigated the structure of the Chinese Material Value Scale (MVS). A two-factor structure, rather than the original three-factor structure, was proposed for China by means of confirmatory factor analysis.
Jiangqun Liao, Lei Wang
doaj   +1 more source

Demotic possession [PDF]

, 2005
As Allan Brown reports, Robin Hardy regarded The Wicker Man (1973) as an anti-fascist film. As such it fits into the classical liberal political schema, based on Enlightenment thinking that freedom and the democratic distribution of power is a product of
Franks, B.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source