Results 81 to 90 of about 1,079,106 (302)

Animism rather than Shamanism: new approaches to what shamans do (for other animists)

open access: yes, 2010
What shamans do is sometimes said to involve possession by spirits. However, shamanism has also been defined in opposition to spirit possession.
Harvey, Graham
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Religious Possession and Self-Repossession: The Black Nationalist Movements and the Anglophone Caribbean Ritual Plays in the 1960s–1970s

open access: yesReligions
Since achieving political independence in the 1960s, Anglophone Caribbean nations have faced the urgent task of exploring cultural independence. In the socio-cultural sphere, Black nationalism dominated, with Pan-Africanism and Rastafarianism exerting ...
Xin Li, Hongwei Chen
doaj   +1 more source

Possession Syndrome Occurring in a Family: A Case Report [PDF]

open access: yesIndian Journal of Private Psychiatry
Possession may happen under acute stress and is more common in people who are religious and those believe in God. The disorder also happens when someone believes in black magic and feels that someone has cast a spell or done this to him or her.
Rucha Sule   +3 more
doaj   +1 more source

Rethinking Novelty in Patent Law [PDF]

open access: yes, 2011
The novelty requirement seeks to ensure that a patent will not issue if the public already possesses the invention. Although gauging possession is usually straightforward for simple inventions, it can be difficult for those in complex fields like ...
Seymore, Sean B.
core   +3 more sources

"The honor of firing before His Majesty": Patrick Ferguson's will and the Royal Armouries’ Ferguson rifle [PDF]

open access: yes, 2008
Patrick Ferguson (1744-80) designed the first breech-loading rifle to be used by the British Army. In November 2000, the Royal Armouries purchased an early example, formerly in the possession of the Fergusons of Pitfour, descendants of Patrick's younger ...
Gilchrist, M.M.
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

‘To sin in loving virtue’: desire and possession in Measure for Measure

open access: yesSillages Critiques, 2013
This essay offers a startling new reading of Shakespeare’s Angelo as a paradoxical if not tragic hero who discovers in his sudden and inexorable impulse to rape a nun in the dark that desire is always more-or-less demonic – even, and perhaps especially ...
Ewan Fernie
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy