Results 91 to 100 of about 17,042 (345)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Compound Formation in Karachay-Balkar: Implications for the marker –sI

open access: yesDilbilim Araştırmaları Dergisi, 2017
This paper discusses morphological, phonological, semantic and syntactic properties of compound formation in Karachay-Balkar with a special focus on Noun-Noun compounds which surface with or without marker –sI and sheds new light on compound formation in
Aslı Gürer
doaj   +1 more source

Machine Translation of Spanish Personal and Possessive Pronouns Using Anaphora Probabilities

open access: yesConference of the European Chapter of the Association for Computational Linguistics, 2017
We implement a fully probabilistic model to combine the hypotheses of a Spanish anaphora resolution system with those of a Spanish-English machine translation system. The probabilities over antecedents are converted into probabilities for the features of
Andrei Popescu-Belis   +3 more
semanticscholar   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The differences of using possessive adjective and possessive pronoun through truth meaning in the most dangerous game [PDF]

open access: yes, 2019
In this reserach, the writer discusses differences in meaning by using possessive adjective and possessive pronoun through truth meaning in The Most Dangerous Game.
Aprianti, Reza Silvia
core  

POSSESSIVE PRONOUNS IN TETUN TERIK LANGUAGE. [PDF]

open access: yes, 2020
This research is discussedabout possessive pronouns in TetunTerik Language. By doing this research, the researcher intended to know what the possessive pronouns are found in TetunTerikLanguage.This research was focused on the possessive pronouns and ...
BESIN, OKTAVIANUS
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

The possessive in Zulu

open access: yes, 1990
Submitted to the Faculty of Arts in fulfilment of the requirements for Master of Arts in the Department of African Languages at the University of Zululand, 1990.This study is a review of the Possessive in Zulu. Many grammarians that have dealt with the
Sabelo, Nonhlanhla Omic
core  

Possessive Processing in Bilingual Comprehension

open access: yesLanguage Learning, 2022
Sol Lago   +3 more
semanticscholar   +1 more source

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