Results 81 to 90 of about 17,042 (345)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
, 1996 . The starting point of this paper is the apparent semantic symmetry between English and French pairs of examples like The name Mary, uses is not hers,/The name Mary, uses is not her, own and Le nom que Mariei utilise n est pas a ellezLe nom que Mariez ...
Anne Zribi-Hertz
core +1 more source
The Possessive Investment in White Sociology
Sociology of Race and Ethnicity, 2018 In this feature review we explore the idea that the discipline is collectively, possessively invested in a particular version of itself—white sociology. We think through some of the key elements of this investment, its consequences, and explore possible ...
D. Brunsma, Jennifer Padilla Wyse
semanticscholar +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Adnominal and predicative possessive constructions in Melanesian languages
, 1983 According to the present state of research, there seems to be no language which shows possessive classifiers and possessive verbs corresponding to English "to have" at the same time. In classifier languages predicative possession is expressed by verbless
Mosel, Ulrike
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Possessive Adjectives and Possessive Pronouns
, 2014 Este chart ejemplifica la diferencia entre un "possessive adjective" y un "possessive pronoun"; así como la correcta construcción de una oración con ambos elementos ...
Fajardo Santana, Yolanda
core
, 2012 The paper analyses the application of grammar knowledge representation of Bulgarian inflectional morphology. We present the implementation of inflectional morphology of Bulgarian possessive and reflexive-possessive pronouns using the semantic networks ...
Stoykova, Velislava
core +1 more source