Results 71 to 80 of about 79,172 (282)

Production and processing asymmetries in the acquisition of tense morphology by sequential bilingual children [PDF]

, 2011
This study investigates the production and on-line processing of English tense morphemes by sequential bilingual (L2) Turkish-speaking children with more than three years of exposure to English.
Baayen, Bishop, Chomsky, Dulay, Dunn, Halle, Hawkins, Haznedar, Kilborn, Lardiere, Marinis, Marinis, Oller, Rice, THEODOROS MARINIS, Tsimpli, Tsimpli, Vainikka, VanPatten, VASILIKI CHONDROGIANNI   +19 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Compound Formation in Karachay-Balkar: Implications for the marker –sI

Dilbilim Araştırmaları Dergisi, 2017
This paper discusses morphological, phonological, semantic and syntactic properties of compound formation in Karachay-Balkar with a special focus on Noun-Noun compounds which surface with or without marker –sI and sheds new light on compound formation in
Aslı Gürer
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Predicative possession in Mande languages

Mandenkan
This article discusses the typology of predicative possession in Mande languages and compares the diversity observed in this domain across the Mande language family with that observed elsewhere in the world, in particular in the language families of West
Denis Creissels
doaj   +1 more source

Anaphor resolution and the scope of syntactic constraints [PDF]

, 2005
An anaphor resolution algorithm is presented which relies on a combination of strategies for narrowing down and selecting from antecedent sets for re exive pronouns, nonre exive pronouns, and common nouns. The work focuses on syntactic restrictions which
Stuckardt, Roland
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Universals in possessive morphology

Glossa, 2018
In this paper, we test the hypothesis that possessive pronouns have the same basic structure containing the genitive pronoun, plus, in some languages, some extra structure, as suggested by Caha (2009). In order to unravel the structure of these pronouns,
Jan Don, Yvonne Van Baal
doaj   +2 more sources