Results 151 to 160 of about 7,087,684 (332)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Association of Skeletal Muscle, Body Fat and Frailty With Prolonged Length of Hospital Stay Following Colectomy for Adenocarcinoma: A Pilot Case‐Control Study

Health Care Science, EarlyView.
ABSTRACT Physical fitness is well‐known to be associated with health outcomes. This pilot study examined the impact of different measures of fitness on length of stay following colectomy. A case‐control study was designed to evaluate the effect of skeletal muscle mass, body fat, and frailty measures on post‐operative length of stay (LOS).
Annmarie Butare, Justin Drake, Michael D. Honaker   +2 more
wiley   +1 more source

Sarcopenia as a severe organ failure, its diagnosing and present therapeutic possibilities [PDF]

Vnitřní lékařství, 2018
Sarcopenia is defined as generalized and progressive age-related loss of skeletal muscle mass, muscle strength and physical performance below a defined threshold. In sarcopenia skeletal muscle mass - the largest body organ - is failing in its function and the term "muscle failure" was suggested.
openaire   +2 more sources

The bidirectional relationship between sarcopenia and disability in China: a longitudinal study from CHARLS

Frontiers in Public Health
ObjectivesSarcopenia and disability represent significant concerns impacting the health of older people. This study aimed to explore the bidirectional relationship between sarcopenia and disability in Chinese older people.MethodsThis study recruited ...
Li Liu, Yan Zhang, Yan Shi, Lanxin Wu, Lixue Meng, Ting Zhao   +5 more
doaj   +1 more source

Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS) [PDF]

, 2019
BACKGROUND Acute liver rejection (ALR), a significant complication of liver transplantation, burdens patients, healthcare payers, and the healthcare providers due to an increase in morbidity, cost, and resources.
Bettcher, Lisa, Ceballos, Brian, Ekser, Burcin, Ellensberg, Matthew, Elliott, Campbell M., Kubal, Chandrashekhar A., Maluccio, Mary A., Mangus, Richard S., Pepin, Robert, Raftery, Daniel, Saxena, Romil, Skill, Nicholas J.   +11 more
core   +1 more source

Nonlinear association of triglyceride‐glucose body mass index with all‐cause mortality in postmenopausal women, a retrospective cohort study: Evidence from the 2001 to 2014 National Health and nutrition examination survey

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The triglyceride‐glucose body mass index (TyG‐BMI) is a novel indicator combining an insulin resistance proxy (TyG index) with adiposity. It remains unclear how TyG‐BMI relates to long‐term mortality risk in postmenopausal women, a group prone to metabolic changes after menopause.
Xiliang Wang, Kaiyue Wang, Chang Tan, Yuexin Yu   +3 more
wiley   +1 more source

Normal Ribosomal Biogenesis but Shortened Protein Synthetic Response to Acute Eccentric Resistance Exercise in Old Skeletal Muscle. [PDF]

, 2018
Anabolic resistance to feeding in aged muscle is well-characterized; however, whether old skeletal muscle is intrinsically resistant to acute mechanical loading is less clear.
Baar, Keith, Baehr, Leslie M, Bodine, Sue C, Chason, Courtney M, Juo, Natalie, Marcotte, George R, West, Daniel WD   +6 more
core  

Serum Concentrations of Myostatin and Myostatin-Interacting Proteins do not differ between young and Scarcopenic elderly men [PDF]

, 2011
Peer ...
A. DeVries, A. Joyson, A. M. Tommasi, A. Ratkevicius, Amin, Baumgartner, C. A. Greig, C. Grierson, Carlson, Clark, D. Crowther, D. M. Reid, F. Gilbert, Gonzalez-Cadavid, GREIG, H. Wackerhage, Hameed, I. Selmer, J. Brady, K. C. H. Fearon, Lakshman, Lauretani, Lee, Lexell, Moreland, Newman, P. Rauchhaus, P. Yaworsky, Pahor, Payette, Rantanen, Rommel, Rosenberg, S. Alesci, Schuelke, Siriett, Streckis, T. Dhanani, T. W. Redpath, Wagner, Wolfe, Zimmers   +41 more
core   +1 more source

Comment on: "Longitudinal Associations Between Baseline Sarcopenia and Knee Osteoarthritis Progression and Risk of Knee Replacement" ‐ Intramuscular Fat Infiltration: A Hidden Covariate in the Sarcopenia–Knee Osteoarthritis Association? Leveraging OAI MRI Data for Adjustment

Arthritis &Rheumatology, Accepted Article.
Huihui Wu, Zhi Wang, Liang Guo
wiley   +1 more source

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

iMeta, EarlyView.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu, Tao Wen, Nan Shang, Penghao Xie, Zhenyu Wang, Hang Li, Shaobo Li, Dequan Zhang   +7 more
wiley   +1 more source