Results 141 to 150 of about 36,908 (274)

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Possibilities of treating sarcopenia in liver cirrhosis with hypoammonemic agents

Meditsinskiy sovet = Medical Council
Introduction. The use of hypoammonemic agents to treat sarcopenia in liver cirrhosis has the potential to positively affect muscle mass, strength and function, given the pathogenetic basis of sarcopenia in liver cirrhosis.Aim. To compare muscle mass, strength and function, as well as capillary blood ammonia levels in patients with decompensated liver ...
A. S. Ostrovskaya, M. V. Maevskaya, K. M. Loban, M. S. Zharkova, M. P. Shapka, E. A. Vasiltsova, Yu. O. Chvileva, V. T. Ivashkin   +7 more
openaire   +1 more source

The Impact of Prehabilitation on Clinical Outcomes in Liver Surgery: A Systematic Review and Meta‐Analysis

World Journal of Surgery, EarlyView.
Major liver surgery is associated with significant physiological stress and a high rate of postoperative complications. Prehabilitation aims to enhance physiological reserve before surgery. Despite the growing volume of liver resections worldwide, the impact of prehabilitation on clinical and economic outcomes in patients undergoing elective liver ...
Lyrics M. Noba, Robyn J. Stiger, Declan F. J. Dunne, Lawrence D. Hayes, Christopher J. Gaffney, Ramani S. Moonesinghe, Ewen M. Harrison   +6 more
wiley   +1 more source

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe, Kohei Yamakawa, Miyu Kobayashi, Yusuke Saigusa, Yukie Yamaguchi   +4 more
wiley   +1 more source

Possibility of clinical intervention by ghrelin to sarcopenia with aging

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2009
Nakazato, Masamitsu, Koshinaka, Keiichi, Toshinai, Koji, Kodama, Tsuyoshi, Ashitani, Jun-Ichi   +4 more
openaire   +3 more sources

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Association between sleep duration and possible sarcopenia in middle-aged and elderly Chinese individuals: evidence from the China health and retirement longitudinal study

BMC Geriatrics
Background Sarcopenia is a common cause of disability in the aging population, and managing sarcopenia is an important step in building intrinsic capacity and promoting healthy aging.
Linfeng Chen, Qingyun Li, Xiaoyun Huang, Zhong Li   +3 more
doaj   +1 more source

Low Free Testosterone Is Independently Associated With Long‐Term Mortality in Men With Chronic Spinal Cord Injury

Andrology, EarlyView.
ABSTRACT Background Testosterone deficiency is highly prevalent in men with chronic spinal cord injury (SCI) and is associated with obesity, sarcopenia, systemic inflammation, and metabolic dysfunction. However, the independent prognostic role of low testosterone in long‐term mortality in this population remains unclear.
D. Tienforti, L. Spagnolo, C. Moretto, G. Terrana, R. Di Geronimo, E. Perfetto, G. Felzani, M. G. Baroni, A. Barbonetti   +8 more
wiley   +1 more source

The association between cognitive function, sleep quality and psychosocial status among older adults with sarcopenia and possible sarcopenia in Kelantan [PDF]

Sarcopenia may influence an elderly’s cognitive ability, quality of sleep and psychosocial condition due to aging. The aim of this study was to explore the association between cognitive function, sleep quality and psychosocial status among older adults ...
Yee, Loo Jia
core  

Glucagon‐like peptide‐1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions

British Journal of Pharmacology, EarlyView.
Abstract Gastric inhibitory polypeptide (GIP)/Glucagon‐like peptide‐1 (GLP‐1) receptor agonists are increasingly prescribed for the management of obesity and type 2 diabetes, yet research pertinent to their effects on muscle health is limited. Considering the central role of muscle strength as a sarcopenia component, this article summarizes emerging ...
Konstantinos Prokopidis
wiley   +1 more source