Sarcopenia and the frailty progression among Chinese: a longitudinal study
IntroductionPrevious studies primarily focused on baseline sarcopenia status, neglecting changes over time. This study aims to explore the association between changes in sarcopenia status and frailty progression, hypothesizing that transitions to ...
Xingyu Mu +4 more
doaj +1 more source
Sarcopenia - Endocrinological and neurological aspects. [PDF]
Sarcopenia in geriatric patients is often associated with or even caused by changes of the endocrine and nervous system. The multifactorial pathogenesis of sarcopenia and additional multimorbidity in geriatric patients makes it difficult to study ...
Stangl, M.K. +16 more
core +1 more source
ABSTRACT The prognostic effect of concurrent metabolic dysfunction‐associated steatotic liver disease (MASLD) on outcomes for hepatocellular carcinoma (HCC) patients remains unclear. The Prognostic Nutritional Index (PNI) reflects nutritional and inflammatory status and is a well‐known prognostic factor.
Chun‐Ting Ho +10 more
wiley +1 more source
Harnessing immunomodulation to combat sarcopenia: current insights and possible approaches
Sarcopenia is a complex age-associated syndrome of progressive loss of muscle mass and strength. Although this condition is influenced by many factors, age-related changes in immune function including immune cell dynamics, and chronic inflammation contribute to its progression.
Ning Zhang +7 more
openaire +3 more sources
Possible sarcopenia, sarcopenic obesity phenotypes and their association with diabetes: Evidence from LASI wave-1 (2017-18) [PDF]
Aims To assess the prevalence of possible sarcopenia and sarcopenic obesity phenotypes and investigate their association with self-reported diabetes among community-dwelling individuals aged 45 or above.
Chandel, Shivani +3 more
core +1 more source
Sarcopenia: a rising geriatric giant: health and economic outcomes of community-dwelling older adults with sarcopenia [PDF]
Future government policy assumes that elderly people will live at home independently for as long as possible instead of relying on care services. This requires a proactive policy to prevent vulnerability. Elderly people often suffer from poor muscle mass
Mijnarends, Donja Marita
core +1 more source
Sarcopenia as a severe organ failure, its diagnosing and present therapeutic possibilities [PDF]
Sarcopenia is defined as generalized and progressive age-related loss of skeletal muscle mass, muscle strength and physical performance below a defined threshold. In sarcopenia skeletal muscle mass - the largest body organ - is failing in its function and the term "muscle failure" was suggested.
openaire +2 more sources
Unintentional Weight Loss Does Not Predict Poor Outcomes in Zenker Diverticulum
In this study of 427 patients with Zenker's diverticulum, 23.6% had significant unintentional preoperative weight loss. Weight loss was associated with preoperative dysphagia and with both the smallest and largest pouches. Postoperative outcomes were similar in patients with and without weight loss, demonstrating a similar efficacy and safety profile ...
Ari D. Schuman +31 more
wiley +1 more source
Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang +9 more
wiley +1 more source
Senotherapeutics for Knee Osteoarthritis
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source

