Results 61 to 70 of about 6,206,550 (249)

Evaluation of sarcopenia and nutritional status in a cohort of patients affected by hepatocellular carcinoma

, 2023
reservedLa prevalenza di sarcopenia nei pazienti con HCC si riscontra tra il 30% e il 50% dei soggetti,anche se sono necessari studi più approfonditi a riguardo.Tra i fattori che contribuiscono alla patogenesi della sarcopenia vi sono anche la ...
SCAPIN, CHIARA
core  

Risk stratification using sarcopenia status among subjects with metabolic dysfunction-associated fatty liver disease [PDF]

, 2021
Background: Sarcopenia is a significant indicator of the severity of non-alcoholic fatty liver disease. We investigated whether sarcopenia could identify subgroups with different risk of liver fibrosis and atherosclerotic cardiovascular disease (ASCVD ...
안상훈, 이재승, 박준용, 김도영, 김승업, 김범경, 이혜원   +6 more
core   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Abnormal sleep duration is associated with sarcopenia in older Chinese people: A large retrospective cross-sectional study

Open Medicine
Abnormalities in sleep patterns are a common health problem for the older adults. The relationship between sarcopenia and sleep duration in older people is controversial. This research is to examine the association between sleep duration and sarcopenia.
Peng Xilin, Zhou Ruihao, Liu Congqi, Chen Xudong, Zhu Tao, Chen Guo   +5 more
doaj   +1 more source

Health outcomes of sarcopenia: a consensus report by the outcome working group of the Global Leadership Initiative in Sarcopenia (GLIS) [PDF]

The Global Leadership Initiative in Sarcopenia (GLIS) aims to standardize the definition and diagnostic criteria for sarcopenia into one unifying, common classification.
Woo, Jean, Lim, Wee Shiong, Beaudart, Charlotte, Yamada, Yosuke, The Global Leadership Initiative in Sarcopenia (GLIS) group, Duque, Gustavo, von Haehling, Stephan, Sanchez-Rodriguez, Dolores, Alcazar, Julian, Reginster, Jean Yves, Aprahamian, Ivan, Batsis, John A., Reginster, Jean-Yves, Prado, Carla M., Sim, Marc   +14 more
core   +1 more source

Additional file 1 of Plasma acylcarnitine in elderly Taiwanese: as biomarkers of possible sarcopenia and sarcopenia

, 2023
Supplementary Material 1: Figure 1. Study flow diagram. This figure shows the number of participants for metabolites analysis. A total of 491 participants enrolled in this study of which 289 subjects were eligible to participate.
Hung-Yao Ho (479549), Hsiang-Yu Tang (17443798), Chun-Ming Fan (11263397), Chih-Ming Lin (3601799), Han-Fang Liu (17443801), Chi-Jen Lo (407376), Mei-Ling Cheng (536352)   +6 more
core   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Sarcopenia

, 2005
Sarcopenia (Greek; sarcos: flesh, and penia: poverty) is the pronounced muscle loss that affects the aging population. Sareopenia of the leg muscles results in loss of independence and increased morbidity in the elderly.
Erik Edström (7045742)
core   +1 more source

Association of sarcopenia and its prognostic value in symptomatic knee osteoarthritis among older people in China: the first longitudinal evidence from CHARLS

BMC Geriatrics
Background Sarcopenia and knee osteoarthritis (KOA) are two common musculoskeletal disorders, often coexisting in aged population and potentially influencing each other.
Jiaxiang Gao, Mulatibieke Yesihati, Huang Cheng, Tong Li, Ran Ding, Weiguo Wang   +5 more
doaj   +1 more source