Results 61 to 70 of about 14,728,127 (259)

Acute Effects of Squat and Ballistic Jump Exercises on Judo-Specific Performance, Handgrip Strength, and Perceived Exertion in Young Male Judokas

Applied Sciences
This study aimed to examine the acute effects of squat and ballistic jump exercises during warm-ups on judo-specific performance in young male judokas.
Jateen Baruah, Avinash Kharel, Madin Hina, Halil İbrahim Ceylan, Muntean Raul-Ioan, Rohit K. Thapa   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Potentiation with Overspeed for Jump Height Enhancement: An Analysis of Factors Distinguishing Responders from Non-Responders

Applied Sciences
(1) Background: This cross-over study aimed to assess the effectiveness of jump height (JH) enhancement after post-activation performance enhancement (PAPE) protocol based on assisted band jumps and to determine factors distinguishing responders (RS) and
Dawid Koźlenia, Jarosław Domaradzki
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Acute enhancement strategies for countermovement jump performance: a network meta-analysis of different resistance training protocols

Frontiers in Physiology
BackgroundCountermovement jump performance is the gold standard for assessing lower limb power, and even minor improvements can significantly enhance performance in sports such as basketball and volleyball.
Ying Zhou, Ying Zhou, Kaiming Wen, Yulong Sun   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Effects of different rest intervals for optimising the acute performance enhancement of judo-specific performance in young female judokas

Human Movement
Purpose Post-activation performance enhancement (PAPE) is a phenomenon that can improve short-term performance in combat sports like judo. However, the optimal rest interval between conditioning activities and judo performance has not been determined ...
Avinash Kharel, Madin Hina, Jateen Baruah, Premraj Saini, Michal Wilk, Rohit K. Thapa   +5 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source