Results 41 to 50 of about 67,475 (271)

Pre-LTP requires extracellular signal-regulated kinase in the ACC

Molecular Pain, 2016
The extracellular signal-regulated kinase is an important protein kinase for cortical plasticity. Long-term potentiation in the anterior cingulate cortex is believed to play important roles in chronic pain, fear, and anxiety.
Manabu Yamanaka, Zhen Tian, Soroush Darvish-Ghane, Min Zhuo   +3 more
doaj   +1 more source

The effect of combined preconditioning strategies on isokinetic strength in well trained kickboxers

Physical Education of Students, 2018
Background & Study Aim: The use of preconditioning strategies (PconSt) alone has a positive impact on performance. However, it is thought that there will be more impact on the performance of the combined preconditioning strategies, and this is the first ...
A. Yilmaz, V.V. Gurses, M. Gulsen
doaj   +1 more source

The effect of ischemic preconditioning on the of anaerobic performance in female student's athletes [PDF]

فیزیولوژی ورزش و فعالیت بدنی, 2019
Purpose: Recently, effect of ischemic preconditioning (IPC) in sports as an ergogenic aid is taken into consideration. IPC may have positive effects on the athletic performance of individuals, which leads to increased capacity in exercise. So, the aim of
Akram Sharifi Moghadam, Faezeh Naserkhani   +1 more
doaj   +1 more source

Optimizing post activation potentiation for explosive activities in competitive sports [PDF]

Journal of Human Kinetics, 2016
Abstract Post activation potentiation (PAP) has shown improved performance during movements requiring large muscular power output following contractions under near maximal load conditions. PAP can be described as an acute enhancement of performance or an enhancement of factors determining an explosive sports activity following a preload ...
Gołaś, Artur, Maszczyk, Adam, Zajac, Adam, Mikołajec, Kazimierz, Stastny, Petr   +4 more
openaire   +2 more sources

Synaptic tagging and capture : differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation [PDF]

, 2010
Weakly tetanized synapses in area CA1 of the hippocampus that ordinarily display long-term potentiation lasting ~3 h (called early-LTP) will maintain a longer-lasting change in efficacy (late-LTP) if the weak tetanization occurs shortly before or after ...
Okuno, Hiroyuki, Redondo, Roger L., Okuno, Hiroyukki, Dr., Spooner, Patrick A., Bito, Haruhiko, Morris, R. G. M. (Richard G. M.), Frenguelli, Bruno G., Morris, Richard G. M.   +7 more
core   +1 more source

Αcute Effect of Two Different Post-Activation Potentiation Running Protocols on Sprint Performance of Preadolescent Boys

Proceedings, 2019
AIM: Forward and backward sprint are two types of locomotion commonly used in sports. The purpose of the present study was to examine the acute effect of two post-activation potentiation sprint protocols, including the aforementioned types of locomotion,
Dimitrios Petrakis, Eleni Bassa, Anastasia Papavasileiou   +2 more
doaj   +1 more source

Post Activation Potentiation of the Plantarflexors: Implications of Knee Angle Variations. [PDF]

J Hum Kinet, 2017
Abstract Flexing the knee to isolate the single joint soleus from the biarticular gastrocnemius is a strategy for investigating individual plantarflexor’s post activation potentiation (PAP). We investigated the implications of testing plantarflexor PAP at different knee angles and provided indirect quantification of the contribution of ...
Gago P, Arndt A, Ekblom MM.
europepmc   +4 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Acute Effects of Plyometric Exercises on Sprint Performance and Kinematics

Physiologia, 2023
Background: Post-activation potentiation refers to the acute and temporary enhancement of performance in explosive movements after performing a conditioning activity, such as plyometrics.
Maria Zisi, Ioannis Stavridis, Gregory Bogdanis, Gerasimos Terzis, Giorgos Paradisis   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source