Results 51 to 60 of about 7,597,013 (263)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Types and description of most common pre-analytical errors [5].

, 2017
Types and description of most common pre-analytical errors [5].
Dereen Najat (3686854)
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Assessment of hematology laboratory performance in the total testing process using quality indicators and sigma metrics in the northwest of Ethiopia: A cross‐sectional study

Health Science Reports
Background and Aims Assuring laboratory quality by minimizing the magnitude of errors is essential. Therefore, this study aimed to assess hematology laboratory performance in the total testing process using quality indicators and sigma metrics. Methods A
Dereje Mengesha Berta, Mekonnen Grima, Mulugeta Melku, Tiruneh Adane, Elias Chane, Bisrat Birke Teketelew, Aregawi Yalew   +6 more
doaj   +1 more source

MANAGEMENT OF ANALYTICAL & POST-ANALYTICAL ERRORS IN THE LABORATORY

MANAGEMENT OF ANALYTICAL & POST-ANALYTICAL ERRORS IN THE LABORATORY Right Method • Right QC • Right Analysis • Right Result • Right Report 🚨 A laboratory result is only clinically valuable when it is accurate, precise, properly validated, reported promptly and communicated to the correct clinician.
Erhabor, Osaro, Erhabor, Angela
openaire   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Evaluation of Non Conformances in the Total Testing Process of a NABL-accredited Clinical Biochemistry Laboratory: An Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Maintaining quality within clinical laboratories is fundamental to patient safety and reliable diagnosis. Every stage of the Total Testing Process (TTP) from sample collection to result reporting, is prone to errors that can affect both ...
Dharmikkumar Savjibhai Patel, Harshkumar Darji, Khushbu R Panchal, Komal J Rathod   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

PRE-ANALYTICAL ERRORS IN A PERIPHERAL HOSPITAL LABORATORY

Pakistan Armed Forces Medical Journal, 2014
Objective: To analyse pre-analytical errors which account for the major contribution towards laboratory errors. Study Design: Cross-sectional descriptive study.
Zujaja Hina Haroon, Haroon Javaid, Haroon Rashid, Muhammad Tahir, Muhammad Qasim Butt, Nighat Afridi   +5 more
doaj   +2 more sources