Results 91 to 100 of about 21,239 (217)

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

Prediction of small for size syndrome after extended hepatectomy: Tissue characterization by relaxometry, diffusion weighted magnetic resonance imaging and magnetization transfer. [PDF]

PLoS ONE, 2018
This study aimed to monitor the course of liver regeneration by multiparametric magnetic-resonance imaging (MRI) after partial liver resection characterizing Small-for-Size Syndrome (SFSS), which frequently leads to fatal post-hepatectomy liver failure ...
Christian Eberhardt, Moritz C Wurnig, Andrea Wirsching, Cristina Rossi, Idana Feldmane, Mickael Lesurtel, Andreas Boss   +6 more
doaj   +1 more source

Systematic review and meta-analysis of thrombocytopenia as a predictor of post-hepatectomy liver failure [PDF]

HPB, 2019
We performed a systematic review and meta-analysis to assess whether thrombocytopenia constituted a risk factor for post-hepatectomy liver failure (PHLF).We searched MEDLINE and EMBASE from inception until February the 17th, 2018 for studies reporting cases of PHLF in patients with and without thrombocytopenia (defined as a platelet count below 100 or ...
Meyer, Jérémy, Balaphas, Alexandre, Combescure, Christophe, Morel, Philippe, Gonelle-Gispert, Carmen, Buehler, Leo Hans   +5 more
openaire   +4 more sources

Study protocol of the HYPER-LIV01 trial: a multicenter phase II, prospective and randomized study comparing simultaneous portal and hepatic vein embolization to portal vein embolization for hypertrophy of the future liver remnant before major hepatectomy for colo-rectal liver metastases

BMC Cancer, 2020
Background In patients undergoing major liver resection, portal vein embolization (PVE) has been widely used to induce hypertrophy of the non-embolized liver in order to prevent post-hepatectomy liver failure.
Emmanuel Deshayes, Lauranne Piron, Antoine Bouvier, Bruno Lapuyade, Emilie Lermite, Laurent Vervueren, Christophe Laurent, Jean-Baptiste Pinaquy, Patrick Chevallier, Anthony Dohan, Agnès Rode, Christian Sengel, Chloé Guillot, François Quenet, Boris Guiu   +14 more
doaj   +1 more source

Post hepatectomy liver failure – A comprehensive review of current concepts and controversies

Annals of Medicine and Surgery, 2018
Post hepatectomy liver failure (PHLF) comprises of a conundrum of symptoms and signs following major hepatic resections. The pathophysiology essentially revolves around disruption of the normal hepatocyte regeneration and disturbed liver homeostasis. Prompt identification of the pre-operative predictors of PHLF in the form of biochemical parameters and
S. Ray, N.N. Mehta, A. Golhar, S. Nundy
openaire   +2 more sources

Evaluation of Living Liver Donors Using Dual‐Contrast‐Agent Magnetic Resonance Imaging (MRI) and Cholangiopancreatography (MRCP)—Technical Development

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The indications for liver transplantation continue to expand to meet the growing need of patients with end‐stage liver disease and select hepatic malignancies. Living donor liver transplantation allows for access to transplant with recipient outcomes superior to deceased donor liver transplantation.
Anum Aslam, Mishal Mendiratta‐Lala, Reve Chahine, Matthew S. Davenport, Neehar D. Parikh, Hero Hussain, Seth Waits, William Weadock, Christopher Sonnenday   +8 more
wiley   +1 more source

Preoperative Multifrequency MR Elastography for Stratifying Wnt/β‐Catenin Pathway and Microvascular Invasion Phenotypes in Hepatocellular Carcinoma

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The Wnt/β‐catenin signaling pathway and microvascular invasion (MVI) are associated with the prognosis of hepatocellular carcinoma (HCC). Purpose To evaluate the Wnt/β‐catenin pathway and MVI states using preoperative MR elastography (MRE). Study Type Prospective.
Huanhuan Chong, Yuchen Yang, Ruokun Li, Weiwei Rui, Jiahao Zhou, Yikun Wang, Qi Lin, Jing Guo, Huimin Lin, Fuhua Yan   +9 more
wiley   +1 more source

A systematic review of prediction models for post-hepatectomy liver failure in patients undergoing liver surgery

HPB, 2021
The aim of this systematic review is to evaluate the current evidence in the context of clinical prediction model for post-hepatectomy liver failure (PHLF).A systematic search of the English literature for a period from December 2005 to September 2020 was conducted.
Kenji Yoshino, Tomoaki Yoh, Kojiro Taura, Satoru Seo, Ruben Ciria, Javier Briceño-Delgado   +5 more
openaire   +4 more sources

Validation of a surgical model for posthepatectomy liver failure in rats

Animal Models and Experimental Medicine, 2023
Background The upper limit for liver resections in rats is approximately 90%. In the early postoperative phase, mortality increases. The aim of the present study was to validate the rat model of 90% partial hepatectomy (PH) as a model of post‐hepatectomy
Andrea Lund, Michelle Meier, Kasper Jarlhelt Andersen, Marie Ingemann Pedersen, Anders Riegels Knudsen, Jakob Kirkegård, Frank Viborg Mortensen   +6 more
doaj   +1 more source

Specific Items of Enhanced Recovery After Surgery for Liver Surgery in Cirrhotic Patients: A Systematic Review

World Journal of Surgery, EarlyView.
Enhanced Recovery After Surgery (ERAS) pathways have been shown to be safe in patients undergoing hepatectomy. Due to cirrhosis‐induced complications, specific or additional perioperative items might need to be implemented. This study systematically reviewed the literature to assess specific items to be included in future ERAS protocol for the ...
Gaëtan‐Romain Joliat, Constant Delabays, Emilie Uldry, Valérie Addor, David Fuks, Emmanuel Melloul   +5 more
wiley   +1 more source