Results 111 to 120 of about 30,532 (266)
Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John +3 more
core +1 more source
Comparison between preoperative two-dimensional shear wave elastography and indocyanine green clearance test for prediction of post-hepatectomy liver failure [PDF]
Tingting Qiu +8 more
openalex +1 more source
Deep learning has shown promise in predicting postoperative complications, particularly when using image or time‐series data. However, on tabular clinical data such as the NCD, it often underperforms compared to conventional machine learning. Integrating multimodal data may enhance predictive accuracy and interpretability in surgical care.
Ryosuke Fukuyo +4 more
wiley +1 more source
Post-hepatectomy liver failure.
Hepatectomies are among some of the most complex operative interventions performed. Mortality rates after major hepatectomy are as high as 30%, with post-hepatic liver failure (PHLF) representing the major source of morbidity and mortality. We present a review of PHLF, including the current definition, predictive factors, pre-operative risk assessment,
Rondi, Kauffmann, Yuman, Fong
openaire +1 more source
ABSTRACT The therapeutic landscape of hepatocellular carcinoma (HCC) has been transformed by recent advancements in systemic therapies, particularly with the introduction of immune checkpoint inhibitors, expanding treatment options beyond conventional locoregional approaches.
Keiichi Akahoshi +4 more
wiley +1 more source
Background: The ideal treatment approach for colorectal cancer (CRC) with synchronous liver metastases (SCRLM) remains debated. We performed a network meta-analysis (NMA) comparing the 'bowel-first' approach (BFA), simultaneous resection (SIM), and the ...
Berardi, Giammauro +7 more
core +1 more source
Background In patients undergoing major liver resection, portal vein embolization (PVE) has been widely used to induce hypertrophy of the non-embolized liver in order to prevent post-hepatectomy liver failure.
Emmanuel Deshayes +14 more
doaj +1 more source
Unsupervised Machine Learning of MRI Radiomics Features Identifies Two Distinct Subgroups with Different Liver Function Reserve and Risks of Post-Hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma [PDF]
Qiang Wang +10 more
openalex +1 more source
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura +9 more
wiley +1 more source
Post-hepatectomy liver failure after major hepatic surgery: not only size matters [PDF]
To compare the value of functional future liver remnant (functFLR) to established clinical and imaging variables in prediction of post-hepatectomy liver failure (PHLF) after major liver resection.This retrospective, cross-sectional study included 62 patients, who underwent gadoxetic acid enhanced MRI and MDCT within 10 weeks prior to resection of ≥ 4 ...
Ulrika Asenbaum +8 more
openaire +2 more sources

