Results 111 to 120 of about 30,532 (266)

Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]

open access: yes, 2015
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John   +3 more
core   +1 more source

Which Method Best Predicts Postoperative Complications: Deep Learning, Machine Learning, or Conventional Logistic Regression?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Deep learning has shown promise in predicting postoperative complications, particularly when using image or time‐series data. However, on tabular clinical data such as the NCD, it often underperforms compared to conventional machine learning. Integrating multimodal data may enhance predictive accuracy and interpretability in surgical care.
Ryosuke Fukuyo   +4 more
wiley   +1 more source

Post-hepatectomy liver failure.

open access: yesHepatobiliary surgery and nutrition, 2014
Hepatectomies are among some of the most complex operative interventions performed. Mortality rates after major hepatectomy are as high as 30%, with post-hepatic liver failure (PHLF) representing the major source of morbidity and mortality. We present a review of PHLF, including the current definition, predictive factors, pre-operative risk assessment,
Rondi, Kauffmann, Yuman, Fong
openaire   +1 more source

Current Status of Multidisciplinary Treatment Strategies for Hepatocellular Carcinoma in the Era of Advanced Systemic Therapies

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT The therapeutic landscape of hepatocellular carcinoma (HCC) has been transformed by recent advancements in systemic therapies, particularly with the introduction of immune checkpoint inhibitors, expanding treatment options beyond conventional locoregional approaches.
Keiichi Akahoshi   +4 more
wiley   +1 more source

Surgical treatment of stage IV colorectal cancer with synchronous liver metastases : a systematic review and network meta-analysis

open access: yes, 2020
Background: The ideal treatment approach for colorectal cancer (CRC) with synchronous liver metastases (SCRLM) remains debated. We performed a network meta-analysis (NMA) comparing the 'bowel-first' approach (BFA), simultaneous resection (SIM), and the ...
Berardi, Giammauro   +7 more
core   +1 more source

Study protocol of the HYPER-LIV01 trial: a multicenter phase II, prospective and randomized study comparing simultaneous portal and hepatic vein embolization to portal vein embolization for hypertrophy of the future liver remnant before major hepatectomy for colo-rectal liver metastases

open access: yesBMC Cancer, 2020
Background In patients undergoing major liver resection, portal vein embolization (PVE) has been widely used to induce hypertrophy of the non-embolized liver in order to prevent post-hepatectomy liver failure.
Emmanuel Deshayes   +14 more
doaj   +1 more source

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura   +9 more
wiley   +1 more source

Post-hepatectomy liver failure after major hepatic surgery: not only size matters [PDF]

open access: yesEuropean Radiology, 2018
To compare the value of functional future liver remnant (functFLR) to established clinical and imaging variables in prediction of post-hepatectomy liver failure (PHLF) after major liver resection.This retrospective, cross-sectional study included 62 patients, who underwent gadoxetic acid enhanced MRI and MDCT within 10 weeks prior to resection of ≥ 4 ...
Ulrika Asenbaum   +8 more
openaire   +2 more sources

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