Establishing the clinical relevance of grade A post‐hepatectomy liver failure [PDF]
J Surg OncolThe International Study Group of Liver Surgery's criteria stratifies post‐hepatectomy liver failure (PHLF) into grades A, B, and C. The clinical significance of these grades has not been fully established.
Dominic J. Vitello +7 more
semanticscholar +4 more sources
Volume and flow modulation strategies to mitigate post-hepatectomy liver failure [PDF]
Frontiers in Oncology, 2022 IntroductionPost hepatectomy liver failure is the most common cause of death following major hepatic resections with a perioperative mortality rate between 40% to 60%.
Richard Bell +5 more
doaj +4 more sources
Hypophosphatemia as a prognostic tool for post-hepatectomy liver failure: A systematic review [PDF]
World J Gastrointest Surg, 2023 BACKGROUND Post-hepatectomy liver failure (PHLF) is one of the main causes of postoperative mortality and is challenging to predict early in patients after liver resection.
R. Riauka +2 more
semanticscholar +4 more sources
HMGB1-Mediated Cell Death—A Crucial Element in Post-Hepatectomy Liver Failure [PDF]
Int J Mol SciLiver resection (LR) is the primary treatment for hepatic tumors, yet posthepatectomy liver failure (PHLF) remains a significant concern. While the precise etiology of PHLF remains elusive, dysregulated inflammatory processes are pivotal.
Laura Brunnthaler +12 more
semanticscholar +4 more sources
Non-invasive strategies to predict post-hepatectomy liver failure [PDF]
Hepatobiliary Surg Nutrdynamic liver function test. The ability of ICG clearance reflects how the liver can remove substances from the bloodstream. A potential risk factor for PHLF is impaired liver function that can be demonstrated by lower ICG clearance.
Anna Cavazza, M A Heneghan
semanticscholar +4 more sources
Effect of early peri-operative arterial lactate concentration level ratios on post-hepatectomy liver failure [PDF]
Discover OncologyBackground Post-hepatectomy liver failure (PHLF) is a serious complication after hepatectomy and a major cause of death. The current criteria for PHLF diagnosis (ISGLS consensus) require laboratory data of elevated INR level and hyperbilirubinemia on or ...
Dong-Dong Wang +14 more
doaj +3 more sources
Early postoperative serum aspartate aminotransferase for prediction of post-hepatectomy liver failure [PDF]
Perioperative Medicine, 2022 Background Post-hepatectomy liver failure (PHLF) is a serious complication of hepatectomy. The current criteria for PHLF diagnosis (ISGLS consensus) require laboratory data on or after postoperative day (POD) 5, which may delay treatment for patients at ...
Watoo Vassanasiri +6 more
doaj +5 more sources
Influence of cytokines, circulating markers and growth factors on liver regeneration and post-hepatectomy liver failure: a systematic review and meta-analysis [PDF]
Scientific Reports, 2021 The pathophysiology of post-hepatectomy liver failure is not entirely understood but is rooted in the disruption of normal hepatocyte regeneration and homeostasis.
Anastasia Murtha-Lemekhova +5 more
doaj +2 more sources
Predicting Post-Hepatectomy Liver Failure in HCC Patients: A Review of Liver Function Assessment Based on Laboratory Tests Scores [PDF]
Medicina (Kaunas), 2023 The assessment of liver function is crucial in predicting the risk of post-hepatectomy liver failure (PHLF) in patients undergoing liver resection, especially in cases of hepatocellular carcinoma (HCC) which is often associated with cirrhosis.
Alessio Morandi +5 more
semanticscholar +2 more sources
Comparing the accuracy of prediction models to detect clinically relevant post-hepatectomy liver failure early after major hepatectomy [PDF]
Br J Surg, 2023 Background Arterial lactate measurements were recently suggested as an early predictor of clinically relevant post-hepatectomy liver failure (PHLF). This needed to be evaluated in the subgroup of major hepatectomies only. Method This observational cohort
Ruth Baumgartner +6 more
semanticscholar +2 more sources