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Post-hepatectomy liver failure.
Hepatobiliary surgery and nutrition, 2014 Hepatectomies are among some of the most complex operative interventions performed. Mortality rates after major hepatectomy are as high as 30%, with post-hepatic liver failure (PHLF) representing the major source of morbidity and mortality. We present a review of PHLF, including the current definition, predictive factors, pre-operative risk assessment,
Rondi M. Kauffmann, Yuman Fong
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The Role of Immune Cells in Liver Regeneration
Livers, 2023 The liver is the only organ that can regenerate and regain its original tissue-to-body weight ratio within a short period of time after tissue loss.
Yankai Wen
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Mesenchymal Stem Cells Improve Glycometabolism and Liver Regeneration in the Treatment of Post-hepatectomy Liver Failure [PDF]
Frontiers in Physiology, 2019 The mortality rate of post-hepatectomy liver failure (PHLF) remains very high, and liver transplantation is the only effective treatment regimen for PHLF. Cell transplantation is a potential treatment for liver diseases. Previous studies have proved that mesenchymal stem cells (MSCs) have immunomodulatory functions.
Haoran Ding +7 more
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Case Reports in Gastroenterology, 2007 Major resection of cirrhotic livers can result in hepatic failure, but no supportive treatment has been found to be generally effective. We successfully treated a 63-year-old woman with post-hepatectomy liver failure with plasmapheresis.
Shin Hwang +4 more
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Xiehe Yixue Zazhi, 2023 The classical Child-Pugh classification and the model for end-stage liver disease are now widely used in clinics for postoperative assessment of liver failure and prognosis in patients with hepatocellular carcinoma (HCC) treated with radical hepatectomy.
ZHANG Yao +4 more
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Zhongliu Fangzhi Yanjiu, 2018 Objective To explore a new cut-off of remnant liver volume-to-body weight ratio (RLV-BWR) and investigate the relationship between RLV-BWR and post-hepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC) of cirrhotic liver ...
LU Zhan +6 more
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Portal vein embolization with absolute ethanol to induce hypertrophy of the future liver remnant
CVIR Endovascular, 2022 Background Preoperative portal vein embolization (PVE) is widely used prior to major liver resection to reduce the risk of post-hepatectomy liver failure (PHLF). We evaluated the efficacy and safety of PVE using absolute ethanol.
Cositha Santhakumar +5 more
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Plasma Glutamine Concentrations in Liver Failure. [PDF]
PLoS ONE, 2016 Higher than normal plasma glutamine concentration at admission to an intensive care unit is associated with an unfavorable outcome. Very high plasma glutamine levels are sometimes seen in both acute and chronic liver failure.
Gunnel Helling +7 more
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Mortality following transarterial embolization due to hemorrhage after liver venous deprivation
International Journal of Gastrointestinal Intervention, 2022 Liver venous deprivation (LVD) is considered to be a safe and effective method that induces more rapid and important liver hypertrophy before major hepatectomy in comparison with portal vein embolization (PVE) alone.
Thanh Dung Le +5 more
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The impact of post-hepatectomy liver failure on mortality: a population-based study [PDF]
Scandinavian Journal of Gastroenterology, 2018 Post-hepatectomy liver failure (PHLF) is considered a main reason for death after major hepatectomy. The reported PHLF-related mortality differs largely and the data mainly originate from single centers.A retrospective, population-based register study was designed to evaluate the impact of PHLF on 90-day mortality after hepatectomy.All patients who ...
Bengt Isaksson +9 more
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