Results 71 to 80 of about 21,239 (217)

Major Hepatectomies: Outcome and Perspectives from Eastern Nepal [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Liver resection is a widely used surgical procedure for different benign and malignant pathology, which carries a significant morbidity and mortality (5-10%). Post-hepatectomy liver failure and bile leak are the major complications of major
Narendra Pandit, Laligen Awale, Shailesh Adhikary   +2 more
doaj   +1 more source

Portal Vein Embolization: Rationale, Techniques, and Outcomes to Maximize Remnant Liver Hypertrophy with a Focus on Contemporary Strategies

Life, 2023
Hepatectomy remains the gold standard for curative therapy for patients with limited primary or metastatic hepatic tumors as it offers the best survival rates.
Jonathan Charles, Nariman Nezami, Mohammad Loya, Samuel Shube, Cliff Davis, Glenn Hoots, Jamil Shaikh   +6 more
doaj   +1 more source

Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure

Cell Death and Disease, 2021
Hepatectomy is an effective therapeutic strategy for many benign and malignant liver diseases, while the complexity of liver anatomy and the difficulty of operation lead to complications after hepatectomy. Among them, post-hepatectomy liver failure (PHLF)
Jing-lin Wang, Hao-ran Ding, Chen-yan Pan, Xiao-lei Shi, Hao-zhen Ren   +4 more
doaj   +1 more source

Extended Adhesion-Sparing Liver Eversion during Kasai Portoenterostomy for Infants with Biliary Atresia

Children, 2021
Background: Despite the fact that Kasai portoenterostomy (KPE) is the primary treatment for biliary atresia (BA), liver transplantation (LT) remains the ultimate surgery for two-thirds of these patients.
Filippo Parolini, Giovanni Boroni, Pietro Betalli, Maurizio Cheli, Domenico Pinelli, Michele Colledan, Daniele Alberti   +6 more
doaj   +1 more source

Liver venous deprivation for resection of advanced hilar cholangiocarcinoma—a case report and review of the literature

Exploration of Targeted Anti-tumor Therapy, 2022
Hilar cholangiocarcinoma is a rare primary malignancy associated with a dismal prognosis. Currently, complete extended right or left-sided hepatectomy is the primary curative therapy.
Radoslava Stoyanova, Helmut Kopf, Wolfgang Schima, Wolfgang Karl Matzek, Alexander Klaus   +4 more
doaj   +1 more source

Lipidomic signatures of post-hepatectomy liver failure using porcine hepatectomy models [PDF]

Annals of Translational Medicine, 2020
Clinical diagnosis of post-hepatectomy liver failure (PHLF) can only be made on or after the 5th postoperative day. Biomarker for early diagnosis is considered as a critical unmet need.Twenty domestic female crossbreed (Yorkshire-landrace and duroc) pigs underwent sham operation (n=6), 70% (n=7) and 90% (n=7) partial hepatectomy (PH).
Kyung Chul Yoon, Jong Cheol Lee, Yoon Young Choi, Hae A Kim, Dong-Sik Kim, Young-In Yoon, Hye-Sung Jo, Jin-I Seok, Myeong Hee Moon   +8 more
openaire   +3 more sources

Anticipating postoperative complications in hepatobiliary surgery: procalcitonine as predictive factor

Frontiers in Surgery
Background and aimsFew studies have indicated that procalcitonin has a potential role in anticipating postoperative complications of hepatic surgery. Here, we focused on validating the relationship between posthepatectomy and serum procalcitonin as short-
Shouwen Zhao, Yuanyuan Song, Le Zhang, Sunan Shi, Jie Li, Yuping Ma, Yong Liao, Zhongguang Zhen   +7 more
doaj   +1 more source

Approaching Thrombospondin-1 as a Potential Target for Mesenchymal Stromal Cells to Support Liver Regeneration after Partial Hepatectomy in Mouse and Humans

Cells
Extended liver resection carries the risk of post-surgery liver failure involving thrombospondin-1-mediated aggravation of hepatic epithelial plasticity and function.
Lysann Tietze, Madlen Christ, Jiyeon Yu, Peggy Stock, Sandra Nickel, Annelie Schulze, Michael Bartels, Hans-Michael Tautenhahn, Bruno Christ   +8 more
doaj   +1 more source

Noninvasively Assessed Portal Hypertension Grade Predicts Post-Hepatectomy Liver Failure in Patients With HepatocellCarcinoma: A Multicenter Study

Frontiers in Oncology, 2022
PurposeTo determine the predictive value of portal hypertension (PH) for the development of post-hepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC).Patients and methodsThis study enrolled a total of 659 patients with HCC ...
Jitao Wang, Jitao Wang, Zhanguo Zhang, Dong Shang, Jinlong Li, Chengyu Liu, Peng Yu, Mingguang Wang, Dengxiang Liu, Hongrui Miao, Shuang Li, Biao Zhang, Anliang Huang, Yewei Zhang, Shubo Chen, Xiaolong Qi   +15 more
doaj   +1 more source

Predicting liver regeneration following major resection

Scientific Reports, 2022
Breakdown of synthesis, excretion and detoxification defines liver failure. Post-hepatectomy liver failure (PHLF) is specific for liver resection and a rightfully feared complication due to high lethality and limited therapeutic success.
Karolin Dehlke, Linda Krause, Silvana Tyufekchieva, Anastasia Murtha-Lemekhova, Philipp Mayer, Artyom Vlasov, Ursula Klingmüller, Nikola S. Mueller, Katrin Hoffmann   +8 more
doaj   +1 more source