Results 151 to 160 of about 181,131 (286)
Post-stroke cognitive impairment: epidemiology, mechanisms and management.
Annals of translational medicine, 2014 Post-stroke cognitive impairment occurs frequently in the patients with stroke. The prevalence of post-stroke cognitive impairment ranges from 20% to 80%, which varies for the difference between the countries, the races, and the diagnostic criteria.
Jia-Hao, Sun, Lan, Tan, Jin-Tai, Yu
openaire +1 more source
Anatomical Progression of Neuropathology in FTLD‐TDP Type C and Linkage to Annexin A11
Annals of Neurology, EarlyView.Objective Frontotemporal lobar degenerations (FTLD)‐TDP type C (TDP‐C) is distinguished from other FTLD‐TDP subtypes by 3 unique features: (1) invariable onset in the anterior temporal lobe (ATL), (2) phosphorylated TDP‐43 (pTDP) neurites in cortex, and (3) colocalization of all pTDP deposits with annexin A11 (ANXA11).
Allegra Kawles +7 more
wiley +1 more source
Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice
Annals of Neurology, EarlyView.A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi +10 more
wiley +1 more source
Post-stroke cognitive impairment and treatment options
Медицинский совет, 2015 Cognitive impairment is a widespread serious complication of ischemic stroke requiring intensive medication treatment. Citicoline is a medicine with proven efficacy in ischemic stroke and vascular cognitive impairment. The article provides an overview of trials on the use of citicoline in patients with cognitive impairment and vascular dementia.
openaire +1 more source
Annals of Neurology, EarlyView.Objective Plasma biomarkers of Alzheimer's disease (AD) pathology are frequently tested in specialized research settings, which limits the generalizability of findings. Using electronic health records and banked plasma, we evaluated plasma biomarkers—phosphorylated tau 217 (p‐tau217), β‐amyloid 1–42/1–40 (Aβ42/Aβ40) and p‐tau217/Aβ42—in a real‐world ...
Katheryn A.Q. Cousins +12 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas +29 more
wiley +1 more source
Autism Research, EarlyView.ABSTRACT Prominent theories of autism suggest autism‐associated differences in visual‐motor integration (VMI) may disrupt learning of motor and social skills typically acquired by observation and imitation. Supporting these theories, children with autism spectrum disorder (ASD) show robust differences in motor tasks reliant on dynamic VMI (e.g., ball ...
Jonah McLaughlin +3 more
wiley +1 more source
Atypical Visually Guided Precision Grip Control in Middle‐Aged and Older Autistic Adults
Autism Research, EarlyView.ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle‐aged and older autistic adults or how they relate to demographic factors and autistic traits.
Zheng Wang +9 more
wiley +1 more source
Autism Research, EarlyView.ABSTRACT Autistic individuals exhibit altered perceptual and visuomotor behaviors, potentially due to reduced cortical specialization. The current study focuses on handedness, a robust marker of cerebral specialization, which is less right‐biased in autism.
Emily Fewster +2 more
wiley +1 more source
Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks
British Journal of Clinical Pharmacology, EarlyView.The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou +2 more
wiley +1 more source