Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source
A Quasi-Experimental Study of an Online Communication Partner Training Program for Orthoptic Students. [PDF]
Lau S, Power E, French A.
europepmc +1 more source
Paroxysmal slow waves mark ictal networks
Abstract Objective Epilepsy diagnosis and treatment monitoring are hindered by the episodic, heterogeneous expression of seizures and by normal‐appearing scalp electroencephalography (EEG) in many patients. We previously described paroxysmal slow‐wave events (PSWEs), brief epochs of broadband slowing detectable on EEG in people with epilepsy.
Florent J. M. Boyer‐Aymé +13 more
wiley +1 more source
Neuroplastic Mechanisms of Acupuncture in Post-Stroke Motor Recovery: A Randomized Multimodal MRI Trial. [PDF]
Yu X +9 more
europepmc +1 more source
A prospective natural history study protocol for clinical trial readiness in synaptic disorders
Abstract Objective STXBP1‐related disorder (STXBP1‐RD) and SYNGAP1‐related disorder (SYNGAP1‐RD) are two common genetic synaptopathies that are associated with epilepsy, developmental delay, intellectual developmental disorder, and behavioral problems.
Jillian L. McKee +38 more
wiley +1 more source
Abstract Objective Detection of epilepsy‐causing structural brain lesions on magnetic resonance imaging (MRI) is critical for diagnosis, prognosis, and treatment planning in people with epilepsy. We aimed to establish an epilepsy‐directed multisite harmonized 3‐T MRI acquisition protocol for the Australian Epilepsy Project (AEP) and describe the ...
David N. Vaughan +19 more
wiley +1 more source
Effects of Brain-Computer Interface-Controlled Hand Robot Training on Post-Stroke Recovery of Upper Limb Motor Functions: A Meta-Analysis of Dose-Matched Randomized Controlled Trials. [PDF]
Hu S, Wang F, Gao X, Zhi Y, Kim D.
europepmc +1 more source
WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse
Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper +11 more
wiley +1 more source
High-Frequency Repetitive Transcranial Magnetic Stimulation on the Left Parietal Lobe Improves Post-Stroke Memory Impairment: An fNIRS Study. [PDF]
Cai L +7 more
europepmc +1 more source

