Results 151 to 160 of about 152,334 (296)

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Research on Application Protocols of Motor Imagery-Based Brain-Computer Interface for Post-Stroke Functional Rehabilitation

康复学报
Brain-Computer Interface （BCI） constitutes an external interactive control system that bypasses the peripheral neuromuscular system，establishing direct communication pathways for cortical outputs.
Jiang Shanshan, QIU Zhiqing, YOU Tingting, FU Xinyu, CHEN Guanzhou, LI Haoda, LIANG Boyuan, YU Jiani, OU Haining   +8 more
doaj  

Home-based guidance training system with interactive visual feedback using kinect on stroke survivors with moderate to severe motor impairment

Journal of NeuroEngineering and Rehabilitation
The home-based training approach benefits stroke survivors by providing them with an increased amount of training time and greater feasibility in terms of their training schedule, particularly for those with severe motor impairment.
Hsuan-Yu Lu, Xiaoyi Wang, Chengpeng Hu, Cathy Choi-Yin Lau, Raymond Kai-Yu Tong   +4 more
doaj   +1 more source

Integrated Hydrophilic Interdigitated Network for Silicone Rubber via a Gradient Polarity Modification Strategy

Advanced Science, EarlyView.
This work overcomes the long‐standing challenge of hydrophilic modification of silicone rubber via a gradient polarity modification strategy. By constructing a hydrophilic interpenetrating network within cured SR, simultaneous surface‐to‐bulk modification is achieved while enabling monitoring through a Eu3+ complex fluorescent tracer.
Lihui Zhang, Rui Wang, Pingru Su, Yao Kou, Zhengfeng Ma, Hui Tang, Mingying Wang, Lixin Wang, Chunyu Zhou, Shuanhong Ma, Yu Tang, Feng Zhou   +11 more
wiley   +1 more source

On the low dimensionality of behavioral deficits and alterations of brain network connectivity after focal injury [PDF]

, 2018
Corbetta, Maurizio, Shulman, Gordon L., Siegel, Joshua S.   +2 more
core   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Evaluating the Effect of Mirror Therapy on Cognitive Neuroplasticity and Motor Recovery in Stroke Rehabilitation

Allied Medical Research Journal
Background: Stroke commonly leads to significant motor impairments through cortical damage. Mirror therapy (MT), utilizing visual feedback to stimulate motor cortex activity, has shown promise as a neuroplasticity-enhancing intervention for motor ...
Perkash Lal, Satish Kumar, Jeetendar Valecha, Mahrukh Warraich , Aneela Shoukat, Safa Rafaqat   +5 more
doaj  

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source