This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis+5 more
wiley +1 more source
Correction: Novel post-translational modification learning signature reveals B4GALT2 as an immune exclusion regulator in lung adenocarcinoma. [PDF]
europepmc +1 more source
Translational and post-translational modifications of proteins as a new mechanism of action of Alpha-Interferon: Review article [PDF]
Michele Caraglia+7 more
openalex +1 more source
Silicon Nanowire Mats Enable Advanced Bioelectrical Recordings in Primary DRG Cell Cultures
SiNW mat‐based MEA (NW_MEA) enables continuous intracellular recordings from neurons in primary rat DRG cell cultures, identifying C‐fiber nociceptors. Supported by an astrocyte feeder layer, SiNW mat promotes DRG neuron and glial cell growth, preserving in vivo‐like cell characteristics and allowing drug‐modulated activity monitoring.
Ivano Lucarini+12 more
wiley +1 more source
<i>Wolbachia</i> infection confers post-translational modification of glutamic acid decarboxylase and other proteins in <i>D. melanogaster</i>. [PDF]
Boothman SM, Preston S, Minden J.
europepmc +1 more source
Post‐translational Modification of Fibroblast Growth Factor 23 [PDF]
Seiji Fukumoto
openalex +1 more source
Albumin Corona Overturns Long‐Acting Behaviors of Myristic Acid‐Conjugated Quetiapine Nanosuspension
Albumin corona alters surface properties and enhances colloidal stability by overturning pH responsiveness and nano‐aggregation behaviors of long‐acting myristic acid‐conjugated quetiapine nanosuspensions (QMN), resulting in accelerated in vitro and in vivo drug release.
Hy Dinh Nguyen+2 more
wiley +1 more source
Improved prediction of post-translational modification crosstalk within proteins using DeepPCT. [PDF]
Huang YX, Liu R.
europepmc +1 more source
Designing an engineering material that simultaneously promotes the growth of beneficial biological cells while eliminating harmful bacteria is often challenging. However, this study presents a unique carbon coating by manufacturing design capable of achieving both functions, demonstrating strong potential for various applications, including medical ...
Abdul Wasy Zia+8 more
wiley +1 more source