Results 251 to 260 of about 85,477 (330)

Role of novel protein acylation modifications in sepsis. [PDF]

Front Immunol
Wang J, He A, Song L, Jiang W, Xu L, Zheng R, Yu J.   +6 more
europepmc   +1 more source

Structural Variability of Pfam Domains Based on Alphafold2 Predictions

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Understanding the biological functions of proteins is one of the main goals of functional genomics. Such understanding will help control and manipulate biological processes to enhance desirable traits, including improved abiotic and biotic stress resistance in humans, animals, plants, and microbes.
Elly Poretsky, Carson M. Andorf, Taner Z. Sen   +2 more
wiley   +1 more source

Hsp70 and Hsp90 post-translational modifications and translating the chaperone code. [PDF]

Cell Stress Chaperones
Backe SJ, Heritz JA, Mollapour M.
europepmc   +1 more source

Beyond Single Chains: Benchmarking Macromolecular Complex Prediction Methods With the Continuous Automated Model EvaluatiOn (CAMEO)

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Independent, blind assessment of structure prediction methods is essential for establishing state‐of‐the‐art performance, identifying limitations, and guiding future developments. The Continuous Automated Model EvaluatiOn (CAMEO) platform provides weekly, automated benchmarking of structure prediction servers, complementing the biennial ...
Xavier Robin, Peter Škrinjar, Andrew M. Waterhouse, Gabriel Studer, Gerardo Tauriello, Janani Durairaj, Torsten Schwede   +6 more
wiley   +1 more source

Practical Outcomes From CASP16 for Users in Need of Biomolecular Structure Prediction

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The 16th Critical Assessment of Structure Prediction benchmarked advancements in biomolecular modeling, particularly in the context of AlphaFold 2 and 3 systems. Protein monomer and domain prediction is largely solved, with barely any space for further improvements at the backbone level except for very specific details, irregular secondary ...
Luciano A. Abriata, Matteo Dal Peraro
wiley   +1 more source

From slit diaphragm to autoantigen formation: a SUMOylation-based perspective on minimal change disease. [PDF]

Front Nephrol
Leventoğlu E, Büyükkaragöz B, Bakkaloğlu SA.   +2 more
europepmc   +1 more source

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

Small Methods, EarlyView.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah, Maryam Adelipour, Hyojin Hwang, Reham M. Marzouk, Heejin Lim, Jooyeon Oh, Ji‐Hyun Cha, Jaebeom Lee, Jeongkwon Kim   +8 more
wiley   +1 more source

Post-Translational Modifications of Lipoproteins: Emerging Players Linking Inflammation and Cardiovascular Disease in Rheumatoid Arthritis-A Narrative Review. [PDF]

Int J Mol Sci
Xu C, Rodríguez-Carrio J, Xie Y, Hu F, Chong WM, Hou HW, Dalan R, Leong KP.   +7 more
europepmc   +1 more source

PTM-Psi: A Python package to facilitate the computational investigation of post-translational modification on protein structures and their impacts on dynamics and functions

Margaret S. Cheung, Daniel Mejı́a-Rodrı́guez, Ho Shin Kim, Natalie Sadler, Xiaolu Li, Pavlo Bohutskyi, Marat Valiev, Weijun Qian   +7 more
openalex   +1 more source

STN1 Shields CTC1 From TRIM32‐Mediated Ubiquitination to Prevent Cellular Aging

Aging Cell, EarlyView.
STN1 safeguards CTC1 from TRIM32‐mediated ubiquitin‐proteasome degradation, thereby preserving CST complex integrity and its roles in telomere maintenance, DNA replication, and DNA damage repair. ABSTRACT The CST (CTC1‐STN1‐TEN1) complex, a single‐stranded DNA (ssDNA) binding complex, is essential for telomere maintenance and genome stability ...
Yina Lan, Xiaole Liang, Guotao Kuang, Tengfei Ma, Fangyingnan Zhang, Zaoli Huang, Huan Wang, Zhenhua Luo, Xuyang Feng   +8 more
wiley   +1 more source