Objective To examine whether white matter hyperintensities (WMHs) and cerebral microbleeds (CMBs) are more prevalent in people with persistent post-traumatic headache attributed to mild traumatic brain injury (TBI), compared with healthy controls ...
Håkan Ashina +9 more
doaj +3 more sources
Persistent post-traumatic headache: a migrainous loop or not? The clinical evidence [PDF]
Background Headache is a common complication of traumatic brain injury. The International Headache Society defines post-traumatic headache as a secondary headache attributed to trauma or injury to the head that develops within seven days following trauma.
Alejandro Labastida-Ramírez +15 more
doaj +2 more sources
Objective To investigate whether persistent post-traumatic headache attributed to mild traumatic brain injury (TBI) is associated with more pronounced pericranial tenderness and lower pressure pain thresholds (PPTs) in the head and neck region, compared ...
Håkan Ashina +5 more
doaj +2 more sources
Hypersensitivity to PACAP-38 in post-traumatic headache: a randomized clinical trial. [PDF]
Pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38), known for its role in migraine pathogenesis, has been identified as a novel drug target.
Al-Khazali HM +7 more
europepmc +2 more sources
Patterns of Use and Benefit of Triptans in the Treatment of Acute Headache Worsening in Youth With Post-Traumatic Headache. [PDF]
Background: Triptans are used to treat migraine attacks, but little-to-no evidence supports their use for youth with post-traumatic headache (PTH). This study evaluated patterns of use and benefit of triptans in the treatment of acute headache worsening ...
Shah R +10 more
europepmc +2 more sources
Background Given that post-traumatic headache is one of the most prevalent and long-lasting post-concussion sequelae, causes significant morbidity, and might be associated with slower neurocognitive recovery, we sought to evaluate the use of concussion ...
Olivia Begasse de Dhaem +4 more
doaj +2 more sources
A High Omega-3, Low Omega-6 Diet Reduces Headache Frequency and Intensity in Persistent Post-Traumatic Headache: A Randomized Trial. [PDF]
Targeted manipulation of dietary omega-3 and omega-6 fatty acids has previously been shown to decrease nontraumatic headaches in controlled trials. This study assessed the effects of a diet high in omega-3 fatty acids and low in omega-6 linoleic acid ...
Zamora D +18 more
europepmc +2 more sources
Guidelines of the International Headache Society for controlled trials of pharmacological preventive treatment for persistent post-traumatic headache attributed to mild traumatic brain injury [PDF]
Background Persistent headache attributed to traumatic injury to the head is divided into two subtypes, one attributed to moderate or severe traumatic injury and another attributed to mild traumatic injury (i.e., concussion).
H. Ashina +12 more
semanticscholar +4 more sources
Sensory hypersensitivities are associated with post-traumatic headache-related disability. [PDF]
To examine whether sensory hypersensitivity contributes to headache‐related disability in a secondary analysis of patients with post‐traumatic headache.
Martindale C +4 more
europepmc +2 more sources
Onabotulinumtoxin A for the Treatment of Post-Traumatic Headache: Is It Better than Anti-CGRP Antibodies? [PDF]
Post-traumatic headache (PTH) is a common and debilitating consequence of traumatic brain injury (TBI), often resembling migraine and tension-type headaches.
Pellesi L, Onan D, Martelletti P.
europepmc +2 more sources

