Results 41 to 50 of about 505,813 (305)

From social housing to subsidised housing? accommodating low income households in Europe [PDF]

open access: yes, 2015
There were three main models of social housing in post war Europe: state housing as part of the communist offer; social rented housing as a pillar of the welfare or corporate state; and (limited) support for self- provision and owner-occupation in more ...
Whitehead, Christine M E
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The survival and resurrection of a “Bakema-experiment” in an Amsterdam garden city

open access: yesDocomomo Journal, 2021
There is a hidden gem in the Amsterdam garden cities. Jaap Bakema was the founder of an experiment in the 1950s. A piece of “Rotterdam in Amsterdam.” Based on the philosophy of an open society and the human scale.
Tim Nagtegaal
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

President Alemán Urban Housing Project

open access: yesDocomomo Journal, 2021
The Centro Urbano Presidente Alemán, inaugurated in 1949, was a pioneer in more ways than one and can be considered as one of the most transcendent works of Mario Pani.
Louise Noelle
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

From Ideal Proposals to Serial Developments: Victor Bourgeois’s Schemes in the Light of Post-War Developments in Brussels

open access: yesUrban Planning, 2019
Three essential elements of modernism consolidated through war: a centralised welfare state, a serial industrial apparatus and, often, a territorial tabula rasa.
Gérald Ledent
doaj   +1 more source

The Death of a Client: The End of The English Housing Estate [PDF]

open access: yes, 2016
Journal article with photographs by author, exploring the political project behind the post-war housing estates of London using the exemplary projects in the London Borough of Camden as a case study. The article takes two well-known projects by architect
Hughes, Beth
core  

Post-disaster housing and management in Malaysia: a literature review [PDF]

open access: yes, 2013
Purpose – Malaysia is still in the process of reorganising and restructuring disaster management policy, learning from the national and international experiences.
O'Keefe, Phil, Roosli, Ruhizal
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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