Results 51 to 60 of about 505,813 (305)

La lingua perduta delle gru

open access: yesAnd, 2022
Il 28 febbraio 1949 il Parlamento italiano rende legge il progetto Provvedimenti per incrementare l’occupazione operaia, agevolando la costruzione di case per lavoratori, presentato al Consiglio nel luglio dell’anno precedente dal ministro democristiano
Valter Scelsi
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Milestones of prefab panel construction at Ukraine: Historical Evolution and Technological Modernization [PDF]

open access: yesE3S Web of Conferences
The aim of this paper is a chronological analysis of the development of prefabricated panel technology in Ukraine, which emerged in response to the urgent post-war need for affordable housing and continues to play a significant role in the country's ...
Voloshchuk Dariia   +2 more
doaj   +1 more source

Prospects for German Post-War Single Family Home Neighborhoods. Case Studies in Five Western German Federal States [PDF]

open access: yes, 2016
Germany is one of the Western European countries with the most apparent effects of demographic change (United Nations 2011). Its population has been declining since 2003 and, under the assumption that this trend will continue, could decrease by a ...
Berndgen-Kaiser, Andrea
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Managing housing needs in post conflict housing reconstruction in Sri Lanka: gaps versus recommendations [PDF]

open access: yes, 2016
Addressing housing needs in post conflict housing reconstruction leads to successful housing reconstruction. As part of a study of investigating how the housing needs can be effectively addressed in post conflict housing reconstruction, this paper ...
Anand P. B.   +26 more
core   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Development of Housing and Communal Infrastructure of the Kemerovo Region in 1946–1950

open access: yesВестник Кемеровского государственного университета, 2019
The present research features the state of housing and communal infrastructure in the Kemerovo region. The author identifies the patterns and features of its development in 1946–1950.
Zlata V. Borovikova
doaj   +1 more source

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