Results 101 to 110 of about 15,420,023 (304)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

O discurso do movimento #OcupeOCocó e sua luta pela significação nas redes sociais

open access: yesCiências Sociais Unisinos, 2017
The purpose of this article is to analyze the speech #OcupeOCocó, a popular movement in defense of Coco Park, in Fortaleza (Brazil), which emerged on social networks in July 2013, and its struggle for meaning in social networks from posts and users ...
Luciana Correia Barbosa   +2 more
doaj  

NOAA backscatter studies [PDF]

open access: yes
In the past year, NOAA has measured and analyzed another year's worth of backscatter over Boulder, CO. The average profile was computed from 80 satellite observations of backscatter spread throughout the year, using NOAA's CO2 coherent lidar operating at
Post, Madison J.
core   +1 more source

On the structure of graded transitive Lie algebras [PDF]

open access: yes, 2000
We study finite-dimensional Lie algebras ${\mathfrak L}$ of polynomial vector fields in $n$ variables that contain the vector fields $\dfrac{\partial}{\partial x_i} \; (i=1,\ldots, n)$ and $x_1\dfrac{\partial}{\partial x_1}+ \dots + x_n\dfrac ...
Post, G.F.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

La influencia de la carretera Mexicali-San Felipe en la calidad de vida de sus inmediaciones

open access: yesEstudios Sociales, 2015
El presente estudio argumenta que la modernización de la Carretera Federal No. 5 Mexicali- San Felipe ha impactado en el bienestar social de diez localidades aledañas.
Alejandro Mungaray Moctezuma   +1 more
doaj  

A Stochastic Dominance Approach to Spanning [PDF]

open access: yes
We develop a Stochastic Dominance methodology to analyze if new assets expand theinvestment possibilities for rational nonsatiable and risk-averse investors.
Post, G.T.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A crítica pós-moderna: analítica da interação e da sociabilidade

open access: yesCiências Sociais Unisinos, 2007
As one attempts to approach the multiple dimensions of modernity and its nexus with contemporary theoretical debates, one should not omit the different contributions made by the so-called post-modern critique. This article discusses these contributions
Carlos A. Gadea
doaj  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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