Results 11 to 20 of about 2,079,695 (308)

Downregulation of phosphoglycerate mutase 5 improves microglial inflammasome activation after traumatic brain injury

open access: yesCell Death Discovery, 2021
Traumatic brain injury (TBI) is considered as the most common cause of disability and death, and therefore an effective intervention of cascade pathology of secondary brain injury promptly can be a potential therapeutic direction for TBI prognosis ...
Yuhua Chen   +8 more
doaj   +1 more source

THE POST-ACTIVATION EFFECT OF COMBINED RESISTED AND ASSISTED SPRINTS [PDF]

open access: yesJournal of Applied Sports Sciences
Resisted and assisted training methods aim to increase neural activation, or post-activation potentiation (PAP), to enhance sprint performance. A preloaded stimulus causes a temporary performance increase that is more significant than what warm-up alone ...
Darryl Cochrane
doaj   +3 more sources

Cortical excitability and multifidus activation responses to transcranial direct current stimulation in patients with chronic low back pain during remission

open access: yesScientific Reports, 2023
Evidence indicates that patients with chronic low back pain (CLBP) have lumbar multifidus muscle (LM) activation deficit which might be caused by changes in cortical excitability.
Peemongkon Wattananon   +4 more
doaj   +1 more source

In vivo metabolic imaging of Traumatic Brain Injury. [PDF]

open access: yes, 2017
Complex alterations in cerebral energetic metabolism arise after traumatic brain injury (TBI). To date, methods allowing for metabolic evaluation are highly invasive, limiting our understanding of metabolic impairments associated with TBI pathogenesis ...
Chaumeil, Myriam M   +7 more
core   +2 more sources

Visualising apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time [PDF]

open access: yes, 2015
Fluorescence lifetime imaging (FLIM) combined with optical projection tomography (OPT) has the potential to map Förster resonant energy transfer (FRET) readouts in space and time in intact transparent or near transparent live organisms such as zebrafish ...
Alexandrov, Y   +13 more
core   +2 more sources

Temporal and Spatial Dynamics of Inflammasome Activation After Ischemic Stroke

open access: yesFrontiers in Neurology, 2021
Background: The inflammasome represents a highly pro-inflammatory mechanism. It has been identified that inflammasome was activated after ischemic stroke. However, the impact of inflammasomes on stroke outcomes remains contradictory.
Danli Lu   +8 more
doaj   +1 more source

Adiponectin protects against paraquat-induced lung injury by attenuating oxidative/nitrative stress. [PDF]

open access: yes, 2014
The specific mechanisms underlying paraquat (PQ)-induced lung injury remain unknown, which limits understanding of its cytotoxic potential. Although oxidative stress has been established as an important mechanism underlying PQ toxicity, multiple ...
Cao, Yu   +9 more
core   +2 more sources

Biomarkers of Complement and Platelet Activation are not correlated with the One or Twenty-Four Hours Corrected Count Increments in Prophylactically Platelet Transfused Hematological Patients: a Prospective Cohort Study

open access: yesPlatelets, 2022
Platelet transfusion refractoriness is a serious clinical concern that complicates the management of thrombocytopenic patients. Previous studies have suggested a potential role for both complement and platelet activation based on in vitro analyses of ...
Alexander Åkesson   +7 more
doaj   +1 more source

Intermittent theta-burst stimulation rescues dopamine-dependent corticostriatal synaptic plasticity and motor behavior in experimental parkinsonism. Possible role of glial activity. [PDF]

open access: yes, 2017
Background: Recent studies support the therapeutic utility of repetitive transcranial magnetic stimulation in Parkinson's disease (PD), whose progression is correlated with loss of corticostriatal long-term potentiation and long-term depression.
Cacace, Fabrizio   +15 more
core   +2 more sources

Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischemia and acidosis in hippocampal CA1 neurons [PDF]

open access: yes, 2015
The CA1 region of the hippocampus is particularly vulnerable to ischemic damage. While NMDA receptors play a major role in excitotoxicity, it is thought to be exacerbated in this region by two forms of post-ischemic AMPA receptor (AMPAR) plasticity ...
Chrast, R.   +7 more
core   +3 more sources

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