Results 21 to 30 of about 2,079,695 (308)

Electrical modalities beyond pacing for the treatment of heart failure [PDF]

, 2010
In this review, we report on electrical modalities, which do not fit the definition of pacemaker, but increase cardiac performance either by direct application to the heart (e.
Berthold Stegemann, Frits W. Prinzen, Lilian Kornet, Richard N. Cornelussen, Ruth Nicholson Klepfer, Vincent Splett   +5 more
core   +3 more sources

Clinical translation of [18F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer [PDF]

, 2018
Background: Effective anticancer therapy is thought to involve induction of tumour cell death through apoptosis and/or necrosis. [18F]ICMT-11, an isatin sulfonamide caspase-3/7-specific radiotracer, has been developed for PET imaging and shown to have ...
Aboagye, Eric O., Cleator, S., Coombes, R. C., Dubash, S. R., Heinzmann, K., Inglese, M., Kenny, Laura, Kozlowski, K., Lavdas, I., Lewanski, C., Lim, A. K., Masrour, N., Mauri, F., Merchant, S., Rama, N., Steel, J. F., Thornton, A.   +16 more
core   +1 more source

Delayed Azithromycin Treatment Improves Recovery After Mouse Spinal Cord Injury

Frontiers in Cellular Neuroscience, 2019
After spinal cord injury (SCI), macrophages infiltrate into the lesion and can adopt a wide spectrum of activation states. However, the pro-inflammatory, pathological macrophage activation state predominates and contributes to progressive ...
Timothy J. Kopper, Katelyn E. McFarlane, William M. Bailey, Michael B. Orr, Bei Zhang, Bei Zhang, John C. Gensel   +6 more
doaj   +1 more source

EFFECT OF POST ACTIVATION POTENTIAL AND PASSIVE STRETCHING MODEL WARM-UP ON JUMPING PERFORMANCE [PDF]

Sportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2017
The purpose of this study was to investigate the effect of different warm-up protocols (post activation potential model warm-up (PAP) and static stretching model warm-up) on jumping performance in male athletes.
Halit Harmancı, Mihri Barış Karavelioğlu, Adnan Ersoy, Oğuzhan Yüksel, Mustafa Sait Erzeybek, Gizem Başkaya   +5 more
doaj  

A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons. [PDF]

PLoS Biology, 2010
Activation of group I metabotropic glutamate receptors (subtypes mGluR1 and mGluR5) regulates neural activity in a variety of ways. In CA1 pyramidal neurons, activation of group I mGluRs eliminates the post-burst afterhyperpolarization (AHP) and produces
Jin-Yong Park, Stefan Remy, Juan Varela, Donald C Cooper, Sungkwon Chung, Ho-Won Kang, Jung-Ha Lee, Nelson Spruston   +7 more
doaj   +1 more source

Regulation of the NLRP3 Inflammasome by Post-Translational Modifications and Small Molecules

Frontiers in Immunology, 2021
Inflammation is a host protection mechanism that eliminates invasive pathogens from the body. However, chronic inflammation, which occurs repeatedly and continuously over a long period, can directly damage tissues and cause various inflammatory and ...
Jin Kyung Seok, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee   +4 more
doaj   +1 more source

Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. [PDF]

, 2019
The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats.
Crawford, Elena, de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Koob, George F, Messing, Robert O, Pomrenze, Matthew B, Schweitzer, Paul, Simpson, Sierra   +8 more
core   +2 more sources

Eccentric flywheel post-activation potentiation influences swimming start performance kinetics [PDF]

Journal of Sports Sciences, 2018
This study aimed to assess the effects of post-activation potentiation in the strength related variables of a kick start. Thirteen competitive swimmers performed three kick starts after a standardized warm up (denoted USUAL) and another after inducing post-activation through five isotonic repetitions on an eccentric flywheel (denoted PAP). A T-test was
Francisco Cuenca-Fernández, Gracia López-Contreras, Luis Mourão, Karla de Jesus, Kelly de Jesus, Rodrigo Zacca, J. Paulo Vilas-Boas, Ricardo J. Fernandes, Raúl Arellano   +8 more
openaire   +3 more sources

Effects of post-tetanic potentiation induced by whole-body electrostimulation and post-activation potentiation on maximum isometric strength

Biology of Sport, 2022
It is currently unknown the most effective potentiation protocol to increase maximum strength. Hence, we investigated the separated and combined effects of post-tetanic potentiation (PTP) induced by whole-body electrostimulation (WB-EMS) and post-activation potentiation (PAP) induced by voluntary maximum isometric contractions on maximum isometric ...
Manuel Dote-Montero, Ignacio Pelayo-Tejo, Pablo Molina-Garcia, Abraham Carle-Calo, Amador García-Ramos, Luis J. Chirosa-Ríos, Ignacio J. Chirosa-Ríos, Francisco J. Amaro-Gahete   +7 more
openaire   +3 more sources

Glutamate-induced depression of EPSP–spike coupling in rat hippocampal CA1 neurons and modulation by adenosine receptors [PDF]

, 2010
The presence of high concentrations of glutamate in the extracellular fluid following brain trauma or ischaemia may contribute substantially to subsequent impairments of neuronal function.
Alici, Andersen, Baratte, Bazhenov, Behan, Benveniste, Bernard, Bernard, Brunedge, Canhão, Carlier, Cash, Clement, Connick, Costenla, Coulter, Cunha, Cunha, Cunha, Cunha, Dahl, Daoudal, Davies, de Mendonça, de Mendonça, de Mendonça, Englund, Ferguson, Fontinha, Forghani, Frenguelli, Frenguelli, Fujii, Fujii, Greiner, Heurteaux, Hoehn, Hülsmann, Jester, Jones, Kitagawa, Klishin, Kukley, Latini, Latini, Lau, Lee, Limbrick, Liu, Lopes, Macgregor, Manzoni, Moore, Nikbakht, Nishizawa, O’Kane, O’Kane, Pedata, Perez-Pinzon, Pugliese, Pugliese, Ribeiro, Schubert, Schurr, Sebastião, Sebastião, Sekino, Sperlagh, Stone, Stone, Szatkowski, Taube, Vizi, Von Lubitz, Wall, Wallis, Wirkner, Wirkner   +77 more
core   +1 more source