No evidence of family history as a risk factor for herpes zoster in patients with post-herpetic neuralgia [PDF]
Little is known about reactivation of latent varicella zoster virus as herpes zoster in individuals with no underlying immunosuppression. Risk factors include age, sex, ethnicity, exogenous boosting of immunity from varicella contacts, underlying cell ...
Boccia, Mt +5 more
core +1 more source
Antiepileptic drugs for the treatment of neuropathic pain : a systematic review [PDF]
Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study ...
Gay Escoda, Cosme +3 more
core +1 more source
IntroductionPrevious studies have suggested an association between blood inflammation-related factors and postherpetic neuralgia. However, the causal relationship between blood inflammation-related factors and postherpetic neuralgia remains unclear ...
Yu Wang, Tian Jia
doaj +1 more source
Things We Do for No Reason™: Prescribing gabapentinoids for pain
Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel +4 more
wiley +1 more source
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu +3 more
wiley +1 more source
Chronic pain reflects maladaptive network interactions across sensory, salience/affective, and descending modulatory pathways. We review evidence for non‐invasive brain stimulation—rTMS, tES, and low‐intensity focused ultrasound—highlighting modest, variable, and often short‐lived analgesic effects under conventional protocols.
Fabian Broecker, Sven Vanneste
wiley +1 more source
Safety profile of oxcarbazepine: results from a prescription-event monitoring study [PDF]
Purpose: To monitor safety of oxcarbazepine, prescribed in primary care in England, using prescription-event monitoring (PEM). Methods: Postmarketing surveillance using observational cohort technique of PEM.
Buggy, Y. +3 more
core +1 more source
Superficial cervical plexus block for management of herpes zoster neuralgia in the C3 dermatome: a case report [PDF]
INTRODUCTION: Herpes zoster is a well-known reactivating viral disease that gives rise to painful skin lesions. Although this vesicular rash heals up within a few weeks, pain sometimes continues, becoming postherpetic neuralgia.
Doo Sik Kim, Hye Young Shin, Sang Su Kim
core +1 more source
TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy
Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin +14 more
wiley +1 more source
Effect of duration of postherpetic neuralgia on efficacy analyses in a multicenter, randomized, controlled study of NGX-4010, an 8% capsaicin patch evaluated for the treatment of postherpetic neuralgia [PDF]
Background Postherpetic neuralgia (PHN) is a painful and difficult to treat complication of acute herpes zoster. Current treatment options provide only partial relief and are often limited by poor tolerability.
Rauck Richard +4 more
core +1 more source

