Results 51 to 60 of about 1,006,360 (290)

Post-mortem interval of buried homicides in Okuku, Nigeria

Egyptian Journal of Forensic Sciences, 2023
Background Post-mortem interval estimation of carcasses buried in shallow graves is a grey area in Nigerian forensic investigations. Most of the investigations and court decisions on the time of death of concealed homicides are based on assumptions in ...
Darlington Nnamdi Onyejike, Victor Adolf Fischer, Ugochukwu Godfrey Esomonu, Ifeoma Miracle Onyejike   +3 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Estimation of the postmortem interval by non-linear programming in conditions of changing ambient temperature

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
The aim of the study is to evaluate the possibilities of determining the postmortem interval by non-linear programming in conditions of changing ambient temperature.
G. V. Nedugov
doaj   +1 more source

Suitability of miRNA assessment in postmortem interval estimation.

European review for medical and pharmacological sciences, 2021
The aim of this review was to explore recent pieces of evidence focused on the use of miRNAs for PMI estimation both in humans and animal experiments, with particular interest on the best miRNAs to use as reference/target markers in different tissues or biological fluids. MiRNAs are innovative biomarkers used in clinical and research field; they appear
Montanari, E, Giorgetti, R, Busardò, F P, Giorgetti, A, Tagliabracci, A, Alessandrini, F   +5 more
openaire   +3 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Postmortem Interval Assessment Criteria : A Retrospective Study [PDF]

, 2020
Introduction, Materials and Methods : In this study, an analysis of forensic medical reports was conducted in order to define new criteria for postmortem interval (PMI) assessment, to improve the accuracy of its determination by forensic medical experts.
Grygorian, Edgar, Gubin, Mykola, Khosha, Vadym, Olkhovsky, Vasil, Simakova-Yefremian, Ella, Kliuiev, Oleksandr   +5 more
core   +1 more source

Estimation of  Postmorterm Interval by Using Myoglobin Concentration in Blood, Liver And Parotid Glands of Albino Rats

Pakistan Armed Forces Medical Journal
Objective: To determine the postmortem interval (PMI) by estimating myoglobin concentration in blood, liver and parotid gland of albino rats and to compare the postmortem level of myoglobin among blood, liver and parotid gland.
Rabia Nasir, Sadaat Ibrahim, Aatiqa Abbas, Arif Rasheed Malik, Noureen Kashif, Mohsin Munawwar Awan   +5 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Investigation of cardiac troponins in postmortem subjects: comparing antemortem and postmortem levels

, 2005
The limitations of autopsy in the diagnosis of death due to ischemic heart disease are well known. In the living, a simple reliable biochemical assay for cardiac troponins is used in the diagnosis of acute myocardial ischemia.
Collinson, P.O., Davies, S. J., Gaze, D.C.   +2 more
core   +1 more source

Detection of H3K4me3 Identifies NeuroHIV Signatures, Genomic Effects of Methamphetamine and Addiction Pathways in Postmortem HIV+ Brain Specimens that Are Not Amenable to Transcriptome Analysis

Viruses, 2021
Human postmortem specimens are extremely valuable resources for investigating translational hypotheses. Tissue repositories collect clinically assessed specimens from people with and without HIV, including age, viral load, treatments, substance use ...
Liana Basova, Alexander Lindsey, Anne Marie McGovern, Ronald J. Ellis, Maria Cecilia Garibaldi Marcondes   +4 more
doaj   +1 more source