Results 61 to 70 of about 1,006,360 (290)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Postmortem Angiography and the Thanatology of the Vascular System

open access: yes, 2016
Postmortem changes of the human body are well known and broadly described in thanatology. Nevertheless, little is known about the influence of postmortem phenomena on the vascular system.
Egger, C.   +5 more
core   +1 more source

The Effects of the Postmortem Interval on the Alzheimer’s Disease Metabolome [PDF]

open access: yes, 2021
Evaluating the effects of postmortem ischemia on brain metabolites has been a longstanding challenge in ex vivo metabolomic studies. This thesis sought to first evaluate which metabolites are affected by short-term postmortem ischemia in rats, through ...
Sylvestre, Duncan
core   +1 more source

Comparison of Biochemical versus Morphological Changes of Human In-Vitro Stored and Postmortem Blood Specimens during Different Time Intervals [PDF]

open access: yesAin Shams Journal of Forensic Medicine and Clinical Toxicology, 2014
Objectives: Estimation of post mortem interval (PMI) remains one of the most difficult challenges to a medicolegal expert. Postmortem biochemical changes may provide chemical markers to help more accurate determination of the postmortem interval ...
Mohamad Hosam El-Din   +2 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Computed Tomography: The Revolution in Postmortem Angiography

open access: yes, 2016
Multidetector computed tomography (MDCT) is the most widespread tool in modern forensic radiology. Thanks to a short examination time, high spatial resolution, and the possibility of reconstructions in different axes and two and three dimensions, it is ...
Silke Grabherr, Grabherr, S.
core   +1 more source

An Overview on Estimation of Postmortem Interval

open access: yes, 2023
Throughout the history of forensic medicine, the postmortem interval (PMI) has been one of the commonly and thoroughly investigated problems. Despite many decades of research, accuracy in estimation of the time of death has not significantly improved and no single method can be reliably used to accurately estimate the time of death.
openaire   +3 more sources

Postmortem Interval and Diagnostic Performance of the Autopsy Methods [PDF]

open access: yesScientific Reports, 2018
AbstractPostmortem studies, including the complete diagnostic autopsy (CDA) and the minimally invasive autopsy (MIA), an innovative approach to post-mortem sampling and cause of death investigation, are commonly performed within 24 hours after death because the quality of the tissues deteriorates over time.
Juan Carlos Hurtado   +36 more
openaire   +4 more sources

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