Results 61 to 70 of about 2,342,405 (342)

The Future Is Now: Unraveling the Expanding Potential of Human (Necro)Microbiome in Forensic Investigations

open access: yesMicroorganisms, 2023
The relevance of postmortem microbiological examinations has been controversial for decades, but the boom in advanced sequencing techniques over the last decade is increasingly demonstrating their usefulness, namely for the estimation of the postmortem ...
Ana Cláudia-Ferreira   +6 more
doaj   +1 more source

Gambaran Histologik Ginjal Hewan Coba Postmortem [PDF]

open access: yes, 2014
: Estimation of postmortem interval plays some significant roles in medicolegal investigation. This was a descriptive experimental study using one local pig as model. Samples were taken from the right and left kidneys at several time intervals: 0 minute,
Kalangi, S. J. (Sonny)   +2 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Postmortem Changes in Animal Carcasses and Estimation of the Postmortem Interval [PDF]

open access: yesVeterinary Pathology, 2016
A thorough understanding of the physical and chemical changes that occur in the body after death is critical for accurate interpretation of gross and microscopic pathology at autopsy. Furthermore, knowledge of the postmortem processes and the factors that affect them will aid in the estimation of the postmortem interval (PMI). The estimation of the PMI
openaire   +2 more sources

Variation of the intraocular pressure in relation to time of death: Contribution to the determination of the true postmortem interval (PMI) [PDF]

open access: yes, 2019
Introducción: La determinación del momento del fallecimiento, es un dato de singular importancia en Medicina Legal constituyendo por su complejidad en uno de los problemas que necesita evaluación objetiva en la Patología Forense.
Genero, Sebastian   +3 more
core  

The Impact of Submersion on the Quantification of Host and Bacterial DNA [PDF]

open access: yes, 2020
The Impact of Submersion on the Quantification of Host and Bacterial DNA Grace Sprouse, Depts. of Forensic Science and Chemistry, with Dr. Catherine Connon, Dept. of Forensic Science and Dr. Baneshwar Singh, Dept.
Sprouse, Grace
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

İn Vitro Kan Değişimleri ve Postmortem İnterval

open access: yesThe Bulletin of Legal Medicine, 2000
Bu çalışmada, otoliz ve putrefaksiyonıın bir sonucu olarak kan hücrelerinde (lökosit, eritrosit, trombosit) meydana gelen postmortem sayısal değişimler ile bu değişimlerin postmortem interval ile olan ilişkisi incelendi. Araştırma, herhangi bir onkolojik, hematolojik veya infeksiyon hastalığı olmadığı bilinen 20 ile 40 yaşlan arasındaki ölmüş ancak ...
Dokgöz, Halis   +4 more
openaire   +2 more sources

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