Results 151 to 160 of about 60,184 (217)

Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss

Aging Cell, Volume 25, Issue 2, February 2026.
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli, Lucía Casares‐Crespo, Elena Juárez‐Escoto, Helena Mira   +3 more
wiley   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

Cell Proliferation, Volume 59, Issue 2, February 2026.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin, Chong Wang, Sihan Li, Yanyan Wang, Tingting He, Jianwei Jiao, Fen Ji   +6 more
wiley   +1 more source

Ethanol Alters DNMT1/3a/3b Expression Profile, Promotes Persistent DNA Hypomethylation in Human Brain Endothelial Cells and Impairs Late Cortical Angiogenesis

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ethanol exposure alters brain endothelial cell function and blood–brain barrier integrity. In human brain microcapillary endothelial cells (HBMEC) and mouse brain endothelial cells (MBEC) from a prenatal alcohol exposure (PAE) model, ethanol increased DNA methyltransferas‐1 (DNMT1) activity and reduced DNA methylation, affecting DNMT3a/3b, methyl‐CpG ...
Michele Siqueira, Matheus Barros, Paula Lacerda Almeida, Luiza dos Santos Heringer, Henrique Rocha Mendonça, Flávia Carvalho Alcantara Gomes, Joice Stipursky   +6 more
wiley   +1 more source

Impact of Mesenchymal Stromal Cell Delivery Through Cardiopulmonary Bypass on Postnatal Neurogenesis. [PDF]

Ann Thorac Surg, 2020
Maeda T, Sarkislali K, Leonetti C, Kapani N, Dhari Z, Al Haj I, Ulrey R, Hanley PJ, Jonas RA, Ishibashi N.   +9 more
europepmc   +1 more source

Development and postnatal neurogenesis in the retina: a comparison between altricial and precocial bird species.

Neural Regen Res, 2021
Alvarez-Hernan G, de Mera-Rodríguez JA, Gañán Y, Solana-Fajardo J, Martín-Partido G, Rodríguez-León J, Francisco-Morcillo J.   +6 more
europepmc   +1 more source

Postnatal hippocampal neurogenesis in schizophrenia and during adolescence

, 2014
Schizophrenia may result from aberrations in maturational neurodevelopmental processes. While many genetic and environmental factors increase the risk of schizophrenia, it is currently unclear how these factors interact across the course of adolescent development to result in the emergence of the illness during this period.
openaire   +2 more sources

Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus. [PDF]

Nat Commun
Tao L, Teng L, Ge M, Wang Y, Hu C, Chen J, Zhao J, Cheng L, Zhang Z, Qin W, Jia Y, Mi D, Yuan Z, Chen L.   +13 more
europepmc   +1 more source

Effects of selected alkaloids on postnatal neurogenesis - in vivo and in vitro studies - literature review. [PDF]

Psychopharmacology (Berl)
Kwiatkowski B, Biedroń N, Gawryś U, Tochman W, Szklarska A, Luchowska-Kocot D.   +5 more
europepmc   +1 more source

Atg5 in microglia regulates sex-specific effects on postnatal neurogenesis in Alzheimer's disease. [PDF]

NPJ Aging
Walter E, Angst G, Bollinger J, Truong L, Ware E, Wohleb ES, Fan Y, Wang C.   +7 more
europepmc   +1 more source

Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors [PDF]

, 2017
Dearborn, Joshua, Kroll, Kristen L, Lewis, Emily M, Patterson, Ethan, Rubin, Joshua B, Sankar, Savita, Tong, Caili, Waller, Laura E, Wozniak, David   +8 more
core   +2 more sources