Results 21 to 30 of about 60,184 (217)

Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. [PDF]

, 2014
Although astrocytes are the most abundant cell type in the central nervous system (CNS), little is known about their molecular specification and differentiation.
Chen, Yidan, Hu, Xuemei, Huang, Hao, Qiu, Mengsheng, Sander, Maike, Teng, Peng, Xie, Binghua, Zhang, Zunyi, Zhao, Xiaofeng, Zheng, Kang, Zhu, Qiang   +10 more
core   +10 more sources

The Effects of Extrinsic and Intrinsic Factors on Neurogenesis

Cells, 2023
In the mammalian brain, neurogenesis is maintained throughout adulthood primarily in two typical niches, the subgranular zone (SGZ) of the dentate gyrus and the subventricular zone (SVZ) of the lateral ventricles and in other nonclassic neurogenic areas (
Mei Jiang, Se Eun Jang, Li Zeng
doaj   +1 more source

Neurogenesis in the postnatal cerebellum after injury [PDF]

International Journal of Developmental Neuroscience, 2018
AbstractThe cerebellum plays major role in motor coordination and learning. It contains half of the neurons in the brain. Thus, deciphering the mechanisms by which cerebellar neurons are generated is essential to understand the cerebellar functions and the pathologies associated with it. In a recent study, Wojcinski et al.
Julia P, Andreotti, Pedro H D M, Prazeres, Luiz A V, Magno, Marco A, Romano-Silva, Akiva, Mintz, Alexander, Birbrair   +5 more
openaire   +2 more sources

GABAB Receptor-Mediated Impairment of Intermediate Progenitor Maturation During Postnatal Hippocampal Neurogenesis of Newborn Rats

Frontiers in Cellular Neuroscience, 2021
The neurotransmitter GABA and its receptors assume essential functions during fetal and postnatal brain development. The last trimester of a human pregnancy and early postnatal life involves a vulnerable period of brain development. In the second half of
Charlotte Gustorff, Till Scheuer, Thomas Schmitz, Christoph Bührer, Stefanie Endesfelder   +4 more
doaj   +1 more source

Postnatal neurogenesis in the human brain

Morphology, 2022
Recently, a lot of data has been gathered which demonstrates neurogenesis in the brain of adult humans. In genetics, findings have been obtained that not only prove, but also elucidate the molecular mechanisms of neurogenesis. In some publications, however, morphology disputes neuronal renewal in adulthood.
Rustam N. Mustafin, Elza K. Khusnutdinova   +1 more
openaire   +1 more source

Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]

, 2007
Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
C.H. Papadimitriou, D. Eppstein, D.D. Sleator, D.E. Knuth, K.M. Lillis, P. Angelini, R. Dhandapani, R.B. Muhammad, T. Leighton   +8 more
core   +4 more sources

Ion channels in postnatal neurogenesis [PDF]

Channels, 2012
Neural stem and progenitor cells (NSC/NPCs) are unspecialized cells found in the adult peri-ventricular and sub-granular zones that are capable of self-renewal, migration, and differentiation into new neurons through the remarkable process of postnatal neurogenesis.
Leigh Anne, Swayne, Leigh, Wicki-Stordeur   +1 more
openaire   +2 more sources

Differential Timing and Coordination of Neurogenesis and Astrogenesis in Developing Mouse Hippocampal Subregions

Brain Sciences, 2020
Neocortical development has been extensively studied and therefore is the basis of our understanding of mammalian brain development. One fundamental principle of neocortical development is that neurogenesis and gliogenesis are temporally segregated ...
Allison M. Bond, Daniel A. Berg, Stephanie Lee, Alan S. Garcia-Epelboim, Vijay S. Adusumilli, Guo-li Ming, Hongjun Song   +6 more
doaj   +1 more source

Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods

eLife, 2021
The transcription factor activating protein two gamma (AP2γ) is an important regulator of neurogenesis both during embryonic development as well as in the postnatal brain, but its role for neurophysiology and behavior at distinct postnatal periods is ...
Eduardo Loureiro-Campos, António Mateus-Pinheiro, Patrícia Patrício, Carina Soares-Cunha, Joana Silva, Vanessa Morais Sardinha, Bárbara Mendes-Pinheiro, Tiago Silveira-Rosa, Ana Verónica Domingues, Ana João Rodrigues, João Oliveira, Nuno Sousa, Nuno Dinis Alves, Luísa Pinto   +13 more
doaj   +1 more source

A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression [PDF]

, 2015
Long non-coding natural antisense transcripts (NATs) are widespread in eukaryotic species. Although recent studies indicate that long NATs are engaged in the regulation of gene expression, the precise functional roles of the vast majority of them are ...
AC Thénié, B Holmqvist, B Kuzin, B Moreno-Lopez, BL Sopher, C-H Cheng, D Dahary, DS Bredt, E Ciani, E Pavesi, GB Robb, J Chen, J Garthwaite, J-T Li, JB Kelley, JE Fish, JH Brann, K Matsui, KY Kwan, L Zhou, MA Faghihi, MA Packer, ME Evangelopoulos, ME Evangelopoulos, MHT Ling, N Peunova, P Ogilvie, RG Tremblay, S Hindley, S Korneev, SA Korneev, SA Korneev, SA Korneev, SA Korneev, SM Gibbs, SR Vincent, U Forstermann, V Calabrese, Y Zhang   +38 more
core   +1 more source